ID C9ZEH2_STRSW Unreviewed; 530 AA.
AC C9ZEH2;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Putative substrate-CoA ligase {ECO:0000313|EMBL:CBG67431.1};
GN OrderedLocusNames=SCAB_2131 {ECO:0000313|EMBL:CBG67431.1};
OS Streptomyces scabiei (strain 87.22).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=680198 {ECO:0000313|EMBL:CBG67431.1, ECO:0000313|Proteomes:UP000001444};
RN [1] {ECO:0000313|EMBL:CBG67431.1, ECO:0000313|Proteomes:UP000001444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=87.22 {ECO:0000313|EMBL:CBG67431.1,
RC ECO:0000313|Proteomes:UP000001444};
RX PubMed=20064060; DOI=10.1094/MPMI-23-2-0161;
RA Bignell D.R., Seipke R.F., Huguet-Tapia J.C., Chambers A.H., Parry R.J.,
RA Loria R.;
RT "Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic
RT cluster that contributes to plant-microbe interactions.";
RL Mol. Plant Microbe Interact. 23:161-175(2010).
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DR EMBL; FN554889; CBG67431.1; -; Genomic_DNA.
DR RefSeq; WP_012998168.1; NC_013929.1.
DR AlphaFoldDB; C9ZEH2; -.
DR STRING; 680198.SCAB_2131; -.
DR GeneID; 24306283; -.
DR KEGG; scb:SCAB_2131; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_0_11; -.
DR Proteomes; UP000001444; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd17631; FACL_FadD13-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020459; AMP-binding.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR PRINTS; PR00154; AMPBINDING.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:CBG67431.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001444}.
FT DOMAIN 15..380
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 431..506
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 530 AA; 57168 MW; 8AA8461D29EE0B6F CRC64;
MAAVDISPAT ALHRRAQHPG PPAVVYENRE ITAVELGATV GEFAAGLSEH GLRRGDRIAY
LGLNSVTFLE TLFAAARLGA VFVPLNFRLA ADEVRHILND CGAHTVVVEE GHRELVESIL
HDIPARTRLL VDTDPACPAT GTPAPAWTPL STLRGPHRPV REPVALYDDD LAALMYTSGT
TGRPKGVMLT HGNLWWNAVN VDAVVDTRAD DVNLALAPLF HIGGLNAFTL RTLVRGGTVV
LRRSFEPAQC LRDLVEHRVN TFFAVPAMYA ALARVPGFAD ADLGALRSAI VAGAPVPPQL
IRDYGEVGLS LQQAWGLTET APFATYLPAR LLPEKAGSAG VAMPYTEIRL THPGTGTGIE
EPDTRGEICV RGPNVTSGYW DNPDATRGAF DDMGWFHTGD IAYRDKDGFY HIVDRLKDMI
ISGGENVYPA EVERVLAELP GVLEAAVVGV PDARWGETVL AVLSCAAGAE PTVEEVRAFA
DRYLARYKLP TDVLVIDRLP RNASGKLDKI ELRRWVTARR NAPSTATATA
//
