ID CAH10_BOVIN Reviewed; 328 AA.
AC A0JN41;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE RecName: Full=Carbonic anhydrase-related protein 10;
GN Name=CA10;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Thalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Does not have a catalytic activity.
CC -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC {ECO:0000305}.
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DR EMBL; BC126507; AAI26508.1; -; mRNA.
DR RefSeq; NP_001073077.1; NM_001079609.1.
DR AlphaFoldDB; A0JN41; -.
DR SMR; A0JN41; -.
DR STRING; 9913.ENSBTAP00000046047; -.
DR PaxDb; 9913-ENSBTAP00000046047; -.
DR Ensembl; ENSBTAT00000049111.4; ENSBTAP00000046047.3; ENSBTAG00000034681.4.
DR GeneID; 535917; -.
DR KEGG; bta:535917; -.
DR CTD; 56934; -.
DR VEuPathDB; HostDB:ENSBTAG00000034681; -.
DR VGNC; VGNC:26648; CA10.
DR eggNOG; KOG0382; Eukaryota.
DR GeneTree; ENSGT00940000155223; -.
DR HOGENOM; CLU_039326_7_1_1; -.
DR InParanoid; A0JN41; -.
DR OMA; GKSHSAW; -.
DR OrthoDB; 49814at2759; -.
DR TreeFam; TF352926; -.
DR Proteomes; UP000009136; Chromosome 19.
DR Bgee; ENSBTAG00000034681; Expressed in occipital lobe and 60 other cell types or tissues.
DR ExpressionAtlas; A0JN41; baseline.
DR GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR GO; GO:0016836; F:hydro-lyase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006730; P:one-carbon metabolic process; IBA:GO_Central.
DR CDD; cd03121; alpha_CARP_X_XI_like; 1.
DR Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR InterPro; IPR041878; Alpha_CARP_X/XI.
DR InterPro; IPR001148; CA_dom.
DR InterPro; IPR036398; CA_dom_sf.
DR InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR PANTHER; PTHR18952:SF91; CARBONIC ANHYDRASE-RELATED PROTEIN 10; 1.
DR Pfam; PF00194; Carb_anhydrase; 1.
DR SMART; SM01057; Carb_anhydrase; 1.
DR SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR PROSITE; PS51144; ALPHA_CA_2; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..328
FT /note="Carbonic anhydrase-related protein 10"
FT /id="PRO_0000282868"
FT DOMAIN 31..301
FT /note="Alpha-carbonic anhydrase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01134"
SQ SEQUENCE 328 AA; 37580 MW; 32E1DB0E6A36DF81 CRC64;
MEIVWEVLFL LQANFIVCIS AQQNSPKIHE GWWAYKEVVQ GSFVPVPSFW GLVNSAWNLC
SVGKRQSPVN IETSHMIFDP FLTPLRINTG GRKVSGTMYN TGRHVSLRLD KEHLVNISGG
PMTYSHRLEE IRLHFGSEDS QGSEHLLNGQ AFSGEVQLIH YNHELYTNVT EAAKSPNGLV
VVSIFIKVSD SSNPFLNRML NRDTITRITY KNDAYLLQGL NIEELYPETS SFITYDGSMT
IPPCYETANW IIMNKPVYIT RMQMHSLRLL SQNQPSQIFL SMSDNFRPVQ SLNNRCIRTN
INFSLQGKDC PNNRAQKLQY RVNEWLLK
//