ID CCB24_ARATH Reviewed; 431 AA.
AC Q9SFW6; Q9SGQ4;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 2.
DT 24-JAN-2024, entry version 136.
DE RecName: Full=Cyclin-B2-4;
DE AltName: Full=G2/mitotic-specific cyclin-B2-4;
DE Short=CycB2;4;
GN Name=CYCB2-4; OrderedLocusNames=At1g76310; ORFNames=F15M4.19, T23E18.24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15208425; DOI=10.1104/pp.104.040436;
RA Wang G., Kong H., Sun Y., Zhang X., Zhang W., Altman N., dePamphilis C.W.,
RA Ma H.;
RT "Genome-wide analysis of the cyclin family in Arabidopsis and comparative
RT phylogenetic analysis of plant cyclin-like proteins.";
RL Plant Physiol. 135:1084-1099(2004).
RN [4]
RP INTERACTION WITH SMR11.
RX PubMed=20706207; DOI=10.1038/msb.2010.53;
RA Van Leene J., Hollunder J., Eeckhout D., Persiau G., Van De Slijke E.,
RA Stals H., Van Isterdael G., Verkest A., Neirynck S., Buffel Y., De Bodt S.,
RA Maere S., Laukens K., Pharazyn A., Ferreira P.C.G., Eloy N., Renne C.,
RA Meyer C., Faure J.-D., Steinbrenner J., Beynon J., Larkin J.C.,
RA Van de Peer Y., Hilson P., Kuiper M., De Veylder L., Van Onckelen H.,
RA Inze D., Witters E., De Jaeger G.;
RT "Targeted interactomics reveals a complex core cell cycle machinery in
RT Arabidopsis thaliana.";
RL Mol. Syst. Biol. 6:397-397(2010).
CC -!- SUBUNIT: Interacts with SMR11 (PubMed:20706207).
CC {ECO:0000269|PubMed:20706207}.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin AB subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF16669.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAF17635.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC009978; AAF17635.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC012394; AAF16669.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE35823.1; -; Genomic_DNA.
DR PIR; F96790; F96790.
DR RefSeq; NP_177758.2; NM_106281.6.
DR AlphaFoldDB; Q9SFW6; -.
DR SMR; Q9SFW6; -.
DR BioGRID; 29183; 5.
DR IntAct; Q9SFW6; 13.
DR STRING; 3702.Q9SFW6; -.
DR PaxDb; 3702-AT1G76310-1; -.
DR EnsemblPlants; AT1G76310.1; AT1G76310.1; AT1G76310.
DR GeneID; 843964; -.
DR Gramene; AT1G76310.1; AT1G76310.1; AT1G76310.
DR KEGG; ath:AT1G76310; -.
DR Araport; AT1G76310; -.
DR TAIR; AT1G76310; CYCB2.
DR eggNOG; KOG0653; Eukaryota.
DR HOGENOM; CLU_020695_0_0_1; -.
DR InParanoid; Q9SFW6; -.
DR PhylomeDB; Q9SFW6; -.
DR PRO; PR:Q9SFW6; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SFW6; baseline and differential.
DR Genevisible; Q9SFW6; AT.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0044772; P:mitotic cell cycle phase transition; IEA:InterPro.
DR CDD; cd20567; CYCLIN_AtCycB-like_rpt1; 1.
DR CDD; cd20511; CYCLIN_AtCycB-like_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR046965; Cyclin_A/B-like.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR InterPro; IPR048258; Cyclins_cyclin-box.
DR PANTHER; PTHR10177:SF402; CYCLIN-B2-4; 1.
DR PANTHER; PTHR10177; CYCLINS; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR PIRSF; PIRSF001771; Cyclin_A_B_D_E; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
DR PROSITE; PS00292; CYCLINS; 1.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Cyclin; Reference proteome.
FT CHAIN 1..431
FT /note="Cyclin-B2-4"
FT /id="PRO_0000287015"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 431 AA; 49241 MW; 3778C3E4C66404C0 CRC64;
MGGSDENRHG VIGPMNRQQG GLRGGKVIPT NGQTRRALSN INKNIIGAPV YPCAVKRPFT
EKNGICNKKI PPVPVHRPVT RKFAAQLAEN NLQIHKEETK KPDLISNEAL DRIITDVEEG
DFNEPMFVQH TEAMLEEIDK MEGIEMQDSN DIDAEVEESV MDIDSCDKNN PLSVVEYIND
IYCFYKKNEC RSCVPPNYME NQHDINERMR GILFDWLIEV HYKFELMEET LYLTINLIDR
FLAVHQHIAR KKLQLVGVTA MLLACKYEEV SVPVVDDLIL ISDKAYTRTE ILDMEKLMAN
TLQFNFCLPT PYVFMRRFLK AAQSDKKLEL LSFFMIELCL VEYEMLQYTP SQLAASAIYT
AQSTLKGYED WSKTSEFHSG YTEEALLECS RKMVGLHHKA GTGKLTGVHR KYNTSKFGYA
ARIEPAGFLL L
//
