ID CLPS_MYCTU Reviewed; 101 AA.
AC P9WPC1; L0T929; P67647; Q10642;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=ATP-dependent Clp protease adapter protein ClpS {ECO:0000255|HAMAP-Rule:MF_00302};
GN Name=clpS {ECO:0000255|HAMAP-Rule:MF_00302}; OrderedLocusNames=Rv1331;
GN ORFNames=MTCY130.16;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011445;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- FUNCTION: Involved in the modulation of the specificity of the ClpAP-
CC mediated ATP-dependent protein degradation. {ECO:0000255|HAMAP-
CC Rule:MF_00302}.
CC -!- SUBUNIT: Binds to the N-terminal domain of the chaperone ClpA.
CC {ECO:0000255|HAMAP-Rule:MF_00302}.
CC -!- SIMILARITY: Belongs to the ClpS family. {ECO:0000255|HAMAP-
CC Rule:MF_00302}.
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DR EMBL; AL123456; CCP44089.1; -; Genomic_DNA.
DR PIR; G70770; G70770.
DR RefSeq; NP_215847.1; NC_000962.3.
DR RefSeq; WP_003406906.1; NZ_NVQJ01000031.1.
DR AlphaFoldDB; P9WPC1; -.
DR SMR; P9WPC1; -.
DR STRING; 83332.Rv1331; -.
DR PaxDb; 83332-Rv1331; -.
DR GeneID; 45425309; -.
DR GeneID; 886891; -.
DR KEGG; mtu:Rv1331; -.
DR TubercuList; Rv1331; -.
DR eggNOG; COG2127; Bacteria.
DR InParanoid; P9WPC1; -.
DR OrthoDB; 162238at2; -.
DR PhylomeDB; P9WPC1; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1390.10; -; 1.
DR HAMAP; MF_00302; ClpS; 1.
DR InterPro; IPR022935; ClpS.
DR InterPro; IPR003769; ClpS_core.
DR InterPro; IPR014719; Ribosomal_bL12_C/ClpS-like.
DR Pfam; PF02617; ClpS; 1.
DR SUPFAM; SSF54736; ClpS-like; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..101
FT /note="ATP-dependent Clp protease adapter protein ClpS"
FT /id="PRO_0000215726"
SQ SEQUENCE 101 AA; 11222 MW; D78302CEC5FF5E5D CRC64;
MAVVSAPAKP GTTWQRESAP VDVTDRAWVT IVWDDPVNLM SYVTYVFQKL FGYSEPHATK
LMLQVHNEGK AVVSAGSRES MEVDVSKLHA AGLWATMQQD R
//
