ID CYSE_BUCAI Reviewed; 274 AA.
AC P57162;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2000, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE RecName: Full=Serine acetyltransferase;
DE Short=SAT;
DE EC=2.3.1.30;
GN Name=cysE; OrderedLocusNames=BU054;
OS Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS pisum symbiotic bacterium).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Buchnera.
OX NCBI_TaxID=107806;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=APS;
RX PubMed=10993077; DOI=10.1038/35024074;
RA Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT sp. APS.";
RL Nature 407:81-86(2000).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + L-serine = CoA + O-acetyl-L-serine;
CC Xref=Rhea:RHEA:24560, ChEBI:CHEBI:33384, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288, ChEBI:CHEBI:58340; EC=2.3.1.30;
CC -!- PATHWAY: Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine
CC from L-serine: step 1/2.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC {ECO:0000305}.
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DR EMBL; BA000003; BAB12777.1; -; Genomic_DNA.
DR RefSeq; NP_239891.1; NC_002528.1.
DR RefSeq; WP_009874011.1; NC_002528.1.
DR AlphaFoldDB; P57162; -.
DR SMR; P57162; -.
DR STRING; 563178.BUAP5A_053; -.
DR EnsemblBacteria; BAB12777; BAB12777; BAB12777.
DR KEGG; buc:BU054; -.
DR PATRIC; fig|107806.10.peg.63; -.
DR eggNOG; COG1045; Bacteria.
DR HOGENOM; CLU_051638_0_1_6; -.
DR UniPathway; UPA00136; UER00199.
DR Proteomes; UP000001806; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009001; F:serine O-acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR CDD; cd03354; LbH_SAT; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR Gene3D; 1.10.3130.10; serine acetyltransferase, domain 1; 1.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR018357; Hexapep_transf_CS.
DR InterPro; IPR045304; LbH_SAT.
DR InterPro; IPR010493; Ser_AcTrfase_N.
DR InterPro; IPR042122; Ser_AcTrfase_N_sf.
DR InterPro; IPR005881; Ser_O-AcTrfase.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR NCBIfam; TIGR01172; cysE; 1.
DR NCBIfam; NF041874; EPS_EpsC; 1.
DR PANTHER; PTHR42811; SERINE ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR42811:SF5; SERINE ACETYLTRANSFERASE-RELATED; 1.
DR Pfam; PF00132; Hexapep; 1.
DR Pfam; PF06426; SATase_N; 1.
DR SMART; SM00971; SATase_N; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE 3: Inferred from homology;
KW Acyltransferase; Amino-acid biosynthesis; Cysteine biosynthesis; Cytoplasm;
KW Reference proteome; Repeat; Transferase.
FT CHAIN 1..274
FT /note="Serine acetyltransferase"
FT /id="PRO_0000068666"
SQ SEQUENCE 274 AA; 30165 MW; 553D252F1048B6B1 CRC64;
MCILKISRIW NKILYDVSFL LKKEPILSDF YQSSILQHQS FTSSLSYILS NKLSTSMISE
KKIQGIFDDV YLNDRSILNF IVQDIKAVLK RDPAVNDYLT PLLYLKGFHA LEAYRISHYL
WNTGKKSLSL YLQSRISSEF SVDIHPAAFI GSGVMLDHAT GIVIGEGVTI ENDVSILHSV
TLGGTGKNFS QNRHPTIRKG VVIGAGAKIL GNIEVGSGAK IGAGSIVLKN VPSDVTVVGV
PAKIVSQVSS KKYYSQKKKN SLKYINIFQH GDGI
//
