ID   D0IQ13_ANOCA            Unreviewed;       814 AA.
AC   D0IQ13;
DT   15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2009, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   SubName: Full=Protocadherin alpha 8 unspliced isoform {ECO:0000313|EMBL:DAA06567.1};
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377 {ECO:0000313|EMBL:DAA06567.1};
RN   [1] {ECO:0000313|EMBL:DAA06567.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=19898614; DOI=10.1371/journal.pone.0007614;
RA   Jiang X.J., Li S., Ravi V., Venkatesh B., Yu W.P.;
RT   "Identification and comparative analysis of the protocadherin cluster in a
RT   reptile, the green anole lizard.";
RL   PLoS ONE 4:E7614-E7614(2009).
RN   [2] {ECO:0000313|EMBL:DAA06567.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Jiang X.-J., Li S., Venkatesh B., Yu W.-P.;
RL   Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BK006913; DAA06567.1; -; Genomic_DNA.
DR   AlphaFoldDB; D0IQ13; -.
DR   eggNOG; KOG3594; Eukaryota.
DR   HOGENOM; CLU_006480_0_1_1; -.
DR   OMA; EQRISIY; -.
DR   TreeFam; TF332299; -.
DR   Bgee; ENSACAG00000022186; Expressed in testis and 1 other cell type or tissue.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007155; P:cell adhesion; IBA:GO_Central.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 6.
DR   Gene3D; 2.60.40.60; Cadherins; 6.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR032455; Cadherin_C.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR013164; Cadherin_N.
DR   PANTHER; PTHR24028; CADHERIN-87A; 1.
DR   PANTHER; PTHR24028:SF133; PROTOCADHERIN ALPHA-9; 1.
DR   Pfam; PF00028; Cadherin; 5.
DR   Pfam; PF08266; Cadherin_2; 1.
DR   Pfam; PF16492; Cadherin_C_2; 1.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 6.
DR   SUPFAM; SSF49313; Cadherin-like; 6.
DR   PROSITE; PS00232; CADHERIN_1; 4.
DR   PROSITE; PS50268; CADHERIN_2; 6.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          33..133
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          158..243
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          244..351
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          352..457
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          458..564
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          580..677
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
SQ   SEQUENCE   814 AA;  89569 MW;  1CFAC4E73BEF0ACF CRC64;
     MVAWQNEPVM KQLLQLILLH TAWEMGSGQL HYSVPEESQH GTFVGRIAQD LGLEVSELVP
     RMFRLVAKGL KKDFFEVNVQ NGILFVNSRI DREELCTDNT DCYIHLEVIV DKPLRVFHVE
     VEIRDINDNA PVFPANEQIL SIAEVITPTG TRFPLEGASD ADIGPNALLT YKLRPNDYFS
     VEQKTDGHHN KPLAIVLKKP LDREEIPTHH LLLTATDGGK PELTGTVQLV INVLDTNDNP
     PVFNQSVYMI KLVENAANGT LVIKLNATDL DERTNGEISY FFSAHIAPNF RKIFEINSNT
     GEVTVSGRVD FEARSVYDLQ IVAEDKGNPP LSEHCKLIIE VLDVNDNAPE VSISSLSVPV
     PEDSPLGTVV ALISISDKDS EANGQVTCSL WPTGLPFKLA STFKNYYSLV VAEHLDRENM
     AEYELMVMAH DHGVSSLSAS STVVVPISDI NDNAPAFVQP PYTVFVKENN PPGAHIFTIS
     AFDPDIAENS LISYWIDEKL WPLSSYISVH SESGKLYALQ PLDYEELKLL EFQVNAKDAG
     LPSLCGNATI QVFVVDENDN APAVTGQTED NSILLVVPVP AGHMVGKIHA LDADSGYNAW
     LRYELHEANS GPWRVGLYSG EISTIRSVDE TEGSRNHNLR VLVKDHGKFQ LSATATLSIS
     LVTSAQAIQT NTRLPRTDES SKPKADIVNL YLIIAICSVS SLFLLVVITY VALRCQFQSK
     EPMVYGPGTA TLVCASEVGS WSYSNRHSHI LTGVNGEALA KNDLMVFSPN IPASSENGKQ
     QDLLCGTVSI IHGRFSFLTL GFNTWAVMMT FLSD
//