ID D0LAJ7_GORB4 Unreviewed; 1123 AA.
AC D0LAJ7;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Ribonuclease, Rne/Rng family {ECO:0000313|EMBL:ACY21310.1};
GN OrderedLocusNames=Gbro_2058 {ECO:0000313|EMBL:ACY21310.1};
OS Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / BCRC 13721 / JCM 3198
OS / KCTC 3076 / NBRC 16047 / NCTC 10667) (Rhodococcus bronchialis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=526226 {ECO:0000313|EMBL:ACY21310.1, ECO:0000313|Proteomes:UP000001219};
RN [1] {ECO:0000313|Proteomes:UP000001219}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25592 / DSM 43247 / BCRC 13721 / JCM 3198 / KCTC 3076 /
RC NBRC 16047 / NCTC 10667 {ECO:0000313|Proteomes:UP000001219};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Ovchinnikova G., Saunders E., Brettin T., Detter J.C., Han C., Larimer F.,
RA Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T.,
RA Wu D., Jando M., Schneider S., Goeker M., Klenk H.-P., Eisen J.A.;
RT "The complete chromosome of Gordonia bronchialis DSM 43247.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACY21310.1, ECO:0000313|Proteomes:UP000001219}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25592 / DSM 43247 / BCRC 13721 / JCM 3198 / KCTC 3076 /
RC NBRC 16047 / NCTC 10667 {ECO:0000313|Proteomes:UP000001219};
RX PubMed=21304674;
RA Ivanova N., Sikorski J., Jando M., Lapidus A., Nolan M., Lucas S.,
RA Del Rio T.G., Tice H., Copeland A., Cheng J.F., Chen F., Bruce D.,
RA Goodwin L., Pitluck S., Mavromatis K., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Chain P.,
RA Saunders E., Han C., Detter J.C., Brettin T., Rohde M., Goker M.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P.,
RA Kyrpides N.C.;
RT "Complete genome sequence of Gordonia bronchialis type strain (3410).";
RL Stand. Genomic Sci. 2:19-28(2010).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; CP001802; ACY21310.1; -; Genomic_DNA.
DR RefSeq; WP_012833868.1; NC_013441.1.
DR AlphaFoldDB; D0LAJ7; -.
DR STRING; 526226.Gbro_2058; -.
DR KEGG; gbr:Gbro_2058; -.
DR eggNOG; COG1530; Bacteria.
DR HOGENOM; CLU_003468_2_0_11; -.
DR OrthoDB; 9804278at2; -.
DR Proteomes; UP000001219; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 1.10.10.2480; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR006847; IF2_N.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR Pfam; PF04760; IF2_N; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001219};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 537..620
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 77..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 184..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 926..1123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..330
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..387
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..437
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 944..960
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 966..984
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1007..1027
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1123 AA; 118779 MW; 7DCC772969FA8D2F CRC64;
MTDNGSPADA NAASGAAEEF PSRLRVHALA RILGMTSREV LAHLAELGAE IRSAQSSVDR
ELAQAVADRV RHHVEVDDAS LAAVDATSTE TPPTAPETPT TAPESAPTAP ESAPTAPEDA
PTAPEDAPTA PEDAPTALED APTAPDPTPE TAVTAADRGP ETPSLFSAAS AQYDHPIAGD
VPALAAGPLF LQPQAPEPSA ERTRDTSARA GSASSDIQGG DTKGGEEQNA DDNGADDTDG
HDDAGKDSGD DTESNRNRRR RRGRRGRGRG RGEQGADDQG ADDADEQAGG DQNRADQNRA
DQNGADTVDS GEDTDVTSDG GSDPESEDEK DAGESGARKK AGRPSGKKGK RSKNKKVAEE
DDAGTDDSDA EDTGESDDAE DSDAEADGNG EGSTRRRRRR RRRKGGADAE DASPDDPPNT
VVHEREPRSK RVRDEVQGIS GSTRLEAKRQ RRRDGRDAGR RRPPILTESE FLARREAVDR
VMVVRERGAN SRIAPGTGDD GHEHATPIED YTQVAVLEDG VLVEHFVTTA TSSSMVGNIY
LGRVQNVLPG MEAAFVDIGR GRNGVLYAGE VNWDAAGLDG GSRKIEQALK PGDNVLVQVS
KDPVGHKGAR LTTQISLAGR YLVYVPGGSS TGISRKLPDV ERKRLKQILA KLVPADAGVI
IRTASEGVSA EELGADIARL EAKWRSIDES VTQAKKNSGS AGPKALYEEP DLLVRVVRDL
FNEDFKKLVV EGAKAWNLVE GYVGSVAPDL MDRVEKFEKP HADAPDSFVV HRIDEQLAKA
LDRKVWLPSG GTLIIEHTEA MTVVDVNTGK FTGSGGNLEE TVTRNNLEAA EEIVRQMRLR
DIGGMIIVDF IDMVLESNRD LVLRRLTEAL ARDRTRHQVS EVTSLGLVQM TRKRLGTGLL
EAFSTTCTTC GGRGVIVHAN PVEVRSEEAG RVEGGSKRSR RGKRKPEAAP EHKPAHHPAE
HPMFRAMAAH SHDDPEHVAH DSDAAPDSAA EASDSAAEAS DSAAEASDSA AAASDSTAAA
PESTPKTPES TPTTPPSTSG PAAEGDGSPR RRRRVVRRAA SPTAAPEPMV LTAAPDGQGD
AAPTPVTTFG PVSPTSAESA VAVRRRPRRR SAGRPAGPPP GEQ
//
