ID D0MZX2_PHYIT Unreviewed; 1506 AA.
AC D0MZX2;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Intraflagellar Transport Protein 140 {ECO:0000313|EMBL:EEY65785.1};
GN ORFNames=PITG_03309 {ECO:0000313|EMBL:EEY65785.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY65785.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
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DR EMBL; DS028121; EEY65785.1; -; Genomic_DNA.
DR RefSeq; XP_002906384.1; XM_002906338.1.
DR STRING; 403677.D0MZX2; -.
DR EnsemblProtists; PITG_03309T0; PITG_03309T0; PITG_03309.
DR GeneID; 9464708; -.
DR KEGG; pif:PITG_03309; -.
DR VEuPathDB; FungiDB:PITG_03309; -.
DR eggNOG; KOG3617; Eukaryota.
DR HOGENOM; CLU_001853_1_0_1; -.
DR InParanoid; D0MZX2; -.
DR OMA; DFDLIWN; -.
DR OrthoDB; 5479064at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.470; -; 2.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15722; IFT140/172-RELATED; 1.
DR PANTHER; PTHR15722:SF7; INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF13176; TPR_7; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 28..108
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 95..136
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1425..1506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1438..1453
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1490..1506
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1506 AA; 167479 MW; 59B44553351D2514 CRC64;
MALFYDYNVA VPANLRQICS VWGELDPVLA VALENREIHF FTDEGDKQQG LESYSRSADI
VTMAWQPRGG ALAVGWSDGM VSLWVFNEQA AREVNSPHTS RVCLLKWAPA GNRLMSADEN
GVFAVWKVDS RCQLTLSTQY ARQGSLTHCV FATRPTLSKD SNTKPDHFAQ HSCPQFFFGG
AVGSVHYADD LGHISDIQVL NHAIESMMFY EEQNRLLVIT RAVQLIVYQI GATDGTVKPI
TKVKLSLAGE GSLLESKWAS PGLLAIASGE PLVRFWNIRT EENSVLSLPK SSGLNYNVNN
LSFSPRRRVL VAGTAQGAVF FWRATSFIDS IAQGNADPAN VSYRWDLLFT AEVGRAVTRL
GWSNAHPALY ANTVEGVVIL HEGNMQRALC GDTAVIQVRP KTLSIEKFQD GVQSGVTITQ
SMLEASLRVK GISHDGSTLV IWNGSKAEVY EMKDGDAKMI NQFKCFSSSM VLRGESIYRA
NGNHVEVCNL AGVVKNTISF TEAEGRPAML SLQNKFLAVG TDRGLLRVFD VSRRDPKALG
SMGNLPEAFD EETKCTVMRA ICVNSDGTRI CILADRVEGG LCMREPSNKL YLFQTDLNIY
QQFDFGSSRY PVSVFFDPQE PRLLVCETVK TGNDNLSTAA GGVSRRDLNS DDGLGAGVAG
GNRGSQVSDK EITIIFASNE HGLLMQDSFD LELKYTALLG IQVPRVYFVA KVDSSSSDDS
TTVVHVGRTK TNNPMTKTPT VYDTVSYLRT QIMRDFTGLD KVNNEAKQAL IDFCYFMTVG
NMDEAYRSVK LIENPSVWEN MARMCVKTKR LDVAEVCLGN MGHARGAAAV QEAKKEPEVE
VAIAMVAIQL GLRDDAARLY RECGRYDLVN KLYQACGYWK KAVDVATKRD RIHLKATYHA
LARHYEEMGD LKEAMEAYED AGTHQKDIPR MLFKLGKVDL LQKYVATSSN RDLLIWWAQF
QESQGQFDAA VESYQRAKDY LSIVRVLCFK KDFQAAAKVA QTSGNRAAAY HLARQFEAHN
EVSNAIHFFA SGGCYNHAIR LAKEHRMDAD LMGFALMSKP NDMLDCAAYF EEQREMEKAV
QLYHKGGNVA KALDLCFQAQ LFDELHHLTD ELSGSGNTSP AILKKCADFF IANGHYAKAV
HLCLIGNRLA EALDVCMQQD VKVTDEMAEK MTPPKGDGST APADKKRRTE LLLKLAKCCK
QQGSYHLATK KYTQAGNKLK AMKCLLKSGD TEKVVFFANV SRNAQIFVLA ANYLQNLDWR
NDTEILKNIV VFYTKARAFE QLAAFYAGCA QVEIEEYRDY EKAISALQEA VQVVSKSRAD
GKDALLKRYE KRILLIEQFT VARQQAKHNP KETMDMVTKL LEEPGIEEAI RVGDGYAMLV
EGYYEEGELN KSLETMEEMK RKGLTLKSYV DPRVVEAVQA KLGVSLGDDR RRRPSPSDYK
QGSSSSRPDS REAKPGQPTS RPVSREAHSI RPGSRGAAMS RPNSREDKMG DDEVEDEMEE
DIAEDE
//
