ID D0MZY9_PHYIT Unreviewed; 644 AA.
AC D0MZY9;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Anaphase-promoting complex subunit, putative {ECO:0000313|EMBL:EEY65802.1};
GN ORFNames=PITG_03328 {ECO:0000313|EMBL:EEY65802.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY65802.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- SIMILARITY: Belongs to the APC3/CDC27 family.
CC {ECO:0000256|ARBA:ARBA00038210}.
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DR EMBL; DS028121; EEY65802.1; -; Genomic_DNA.
DR RefSeq; XP_002906401.1; XM_002906355.1.
DR AlphaFoldDB; D0MZY9; -.
DR STRING; 403677.D0MZY9; -.
DR EnsemblProtists; PITG_03328T0; PITG_03328T0; PITG_03328.
DR GeneID; 9464485; -.
DR KEGG; pif:PITG_03328; -.
DR VEuPathDB; FungiDB:PITG_03328; -.
DR eggNOG; KOG1126; Eukaryota.
DR HOGENOM; CLU_008850_1_1_1; -.
DR InParanoid; D0MZY9; -.
DR OMA; CEAWCVA; -.
DR OrthoDB; 152021at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR007192; APC8.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF13; CELL DIVISION CYCLE PROTEIN 27 HOMOLOG; 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF04049; ANAPC8; 1.
DR Pfam; PF00515; TPR_1; 2.
DR Pfam; PF14559; TPR_19; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 4.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT DOMAIN 109..158
FT /note="Cdc23"
FT /evidence="ECO:0000259|Pfam:PF04049"
FT REPEAT 419..452
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 453..486
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 487..520
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 589..622
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 171..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 644 AA; 73292 MW; 70B82C085A279BE1 CRC64;
METALVGQVQ RYLDLYVYDN ARFLAERLVA HHPSEENALL LASCYYRKGQ VDRAVEVLSG
ATRAENRYLL ARCCFQQNKL VEAENALLGG EKCHIDELDA IENVPAGAAG LYLLGRVCRR
GNRRQQAVAC FIKSLEIDPF MWSAYEELCE LGANLEASRF FGTANYFHSS ESQFGDEDDN
NAEDRPTDES FGTPEPPPFF GLGTPKNVLS SEPNTSRPLA YKTPNVNNNN NGNDIHTATV
VKKPRVEDVG APLRQRKAYR RPLADSDEKY RPNARLSFSA AAFDDSPLNP SKLSLGSPTS
PLPTRRLYQD KTLLLRLLTS FGSIYQKVSM YMCGEALEML EQLPASQRAS GWAQQQIGRA
YFEMADYVQA QEVFCALHRA EPHRMDGLDL YSTTLWHLKK EVELSYLAQQ ATDFDKLSCE
AWCVAGNCFS LQKEHDTALA FFQRAIQLDP SFTYAYTLSG HEYVANEDFE KAVNCYRHAI
RTDSRHYNAW YGLGTIYYRQ EKFEFAEYHF KRALEINPRS SLLHCFLGMV LHATHRYDDA
LATLAVAAEL QPLNPQARFQ RANVLITLQQ YEEALEELHV VKNFAPRESS VHFMMGKVAK
KLGRIEEAMK YFILALHFHP KDNNQIKVAI DKINEPDHED DDRM
//
