ID D0N3Q6_PHYIT Unreviewed; 680 AA.
AC D0N3Q6;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Histone deacetylase, putative {ECO:0000313|EMBL:EEY69010.1};
GN ORFNames=PITG_05176 {ECO:0000313|EMBL:EEY69010.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY69010.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
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DR EMBL; DS028124; EEY69010.1; -; Genomic_DNA.
DR RefSeq; XP_002998864.1; XM_002998818.1.
DR AlphaFoldDB; D0N3Q6; -.
DR STRING; 403677.D0N3Q6; -.
DR EnsemblProtists; PITG_05176T0; PITG_05176T0; PITG_05176.
DR GeneID; 9466021; -.
DR KEGG; pif:PITG_05176; -.
DR VEuPathDB; FungiDB:PITG_05176; -.
DR eggNOG; KOG1343; Eukaryota.
DR HOGENOM; CLU_013523_0_0_1; -.
DR InParanoid; D0N3Q6; -.
DR OMA; SEDDYGW; -.
DR OrthoDB; 68880at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR CDD; cd11599; HDAC_classII_2; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 2.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006643}.
FT DOMAIN 232..398
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT DOMAIN 421..622
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 59..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 132..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 75772 MW; 92ADAA8A2EFF8628 CRC64;
MQASGNKPIW CSPSRDDDNQ SQEHVHTLLS LHTPPMMRSP QEKEAARHFD MHNSVISLLS
SSPESSSGSD TSSTGTDRSN GPHYLANIEH PISAHDAHLV VQPPYSNMEY LDNQERYVQE
GKISIPLNTM TQEKVHRKRP APSPVQIRFN PKQPASDSCL STLTGGKSSM LAKLASNLLQ
QLENEATGTL LVYQPTCLDH HNDSHQESRQ RLCVLGGPEG VLHKDRFKDL KWANLNELRP
ARLNDILRVH TIEYIQHLER ACGNLPEQSK KYLVGTLFDK EKGDKELTYD AWLQTKHALK
CFGVGDQPSG GSFDMDSPIS KSSYMAARMA AGAVCHAIDK VLSNETKNAF VVVRPPGHHA
GPNGCVEGEG FHLRPEMCTC GFCLINNVCI GASYAMSNYY TPYYTHPAVS NMASETLVAT
RKRVNVQRVA IVDFDIHHGN GTEEVIRNLI PHKQNYPLPP SWAPVQFSSY KPWRDERDPE
NVFFSSIHLY DDDNFYPCSG VGPHGCSPEL EKSKNVVNLP LKVLGPKYLD ERLKLSSKAK
RSLMEISSKA FRDTVTKKLV PALTKFQPDL IMLSAGFDGH ADDFYYFLSE DDYGWITEQI
TAVAEDCCDG RIISVLEGGY NVVPSKCQRP QPKARKSAIS NFHYAAKMHN RPVDEELNAY
GSLARSVASH VAALMRASQI
//
