ID D0N6M7_PHYIT Unreviewed; 1365 AA.
AC D0N6M7;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=ATP-binding Cassette (ABC) Superfamily {ECO:0000313|EMBL:EEY53226.1};
GN ORFNames=PITG_06863 {ECO:0000313|EMBL:EEY53226.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY53226.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
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DR EMBL; DS028127; EEY53226.1; -; Genomic_DNA.
DR RefSeq; XP_002904844.1; XM_002904798.1.
DR EnsemblProtists; PITG_06863T0; PITG_06863T0; PITG_06863.
DR GeneID; 9463678; -.
DR KEGG; pif:PITG_06863; -.
DR VEuPathDB; FungiDB:PITG_06863; -.
DR eggNOG; KOG0065; Eukaryota.
DR HOGENOM; CLU_000604_35_3_1; -.
DR InParanoid; D0N6M7; -.
DR OMA; AFICYMI; -.
DR OrthoDB; 1384804at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR PANTHER; PTHR19241:SF625; ATP-DEPENDENT PERMEASE PDR10-RELATED; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:EEY53226.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 437..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 539..566
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 586..603
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 670..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1089..1108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1120..1141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1162..1189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1201..1223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1230..1248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1339..1360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 76..342
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 751..992
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1365 AA; 152069 MW; C75F463B5EE08648 CRC64;
MDKKLGLDSA DALMAQGPNA LHSYVADKVQ AAMGKAMPQM EVRFKNLSIS ANVFASSHSD
PKSQLPTLYN CVKKSAAKIN AKNHTAEKGI LKNASGVFKP GTITLLLGQP GSGKSSLMKV
LSGRFPLEKN VTIEGAITFN GVPQTDIMKR LPQFAAYVTQ RDKHFPTLTV TETLQFAHAF
CGGGISNRTE KLLSKGTPEE NTAALEALEA LYAHYPDVVI KQLGLENCKD TIVGNAMLRG
VSGGERKRVT TGEMEFGMKY MTLMDEISTG LDSAATFDII STQRGIAKTL QKTVVIALLQ
PSPEVFELFD DVMILNDGEV MYHGPRDQAV PFFESLGFKC PADRDEADFL LDLGTNQQYG
YEVNLPSEMT HHPRLASEFA EIFRRSSIHE RMLQALDNPH EPALLENVGA HMDPMPEFRR
GFWENTRTLM KRQTMVTLRN TAFIKGRCIM VVLMGLIYSS TFWQVDPTDV QVALGIMFQA
VLFLALGQVS QIPTFMAARD VFYKQRGANF FPTAAYVLAC SVAQIPMAVA ESVIFGSMVY
WMCGFVATAG AFICYMILLI LTNLVFSSWF FLLTAMSPDF HIAKPFATFT VVFFILFAGF
VMAKSTMPGW FVWIYWINPI AWCLRGLAVN QYRAAKFDVC VYEGVNYCAD YNMNMGEYYL
SQYDVPSSKV WVWAAMLFMI ACYALFMALG CYVLEYHRFE SPEHTIVKDK DEESDESYAL
VATPKGSSTS SAERAIALDI GREKNFVPVI LAFQDLWYSV PKPGNPKESI DLLKGISGFA
TPGNMTALMG SSGAGKTTLM DVIAGRKTGG TIKGKILLNG YEANDLAIRR STGYCEQMDI
HSDATTFREA FTFSAFLRQD SSVPDHKKYD SVEEVLDLLD MHDIADQIVR GSSVEQMKRL
TIGVEVAAQP SVLFLDEPTS GLDARSAKLI MDGVRKVADS GRTIVCTIHQ PSSDVFYLFD
HLLLLKRGGE TVFVGELGEK CRKLVEYFES TPGVAPLPDR YNPATWMLEC IGAGVNNGGH
STMDFVEYFK NSQEKRFLDN EMAQEGVTVP APDLPEMIFQ KKRAASSWTQ AKFLTTRFMR
MYWRTPTYNM TRFAIGLFLA LLFGLTYVDV EYVSYQGING GVGMVFMTTL FNGIVSFNGV
LPIASGDRAA FYRERASQTY NSLWYFVGST IAEIPYVFIS CLLFTVIFYP LVGFTGFGTG
VLYWINLSLL VLLQTYMGQL FVYALPSVEV AAIIGVLINS IFFLFMGFNP PAKSIPSGYR
WLYTITPQRY PLSIMMALVF SDCPTEPTWD SNLGQYVNVG SELGCQPVTN LPVTIDHITV
KGYMESVFEM KHDDIWSNFG YVFVFIGALR LLALLSLRYI NHQKR
//
