ID D0N7I0_PHYIT Unreviewed; 1632 AA.
AC D0N7I0;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=UDP-glucose:glycoprotein glucosyltransferase, putative {ECO:0000313|EMBL:EEY53529.1};
GN ORFNames=PITG_07201 {ECO:0000313|EMBL:EEY53529.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY53529.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum lumen
CC {ECO:0000256|ARBA:ARBA00004319}.
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DR EMBL; DS028127; EEY53529.1; -; Genomic_DNA.
DR RefSeq; XP_002905147.1; XM_002905101.1.
DR STRING; 403677.D0N7I0; -.
DR EnsemblProtists; PITG_07201T0; PITG_07201T0; PITG_07201.
DR GeneID; 9465906; -.
DR KEGG; pif:PITG_07201; -.
DR VEuPathDB; FungiDB:PITG_07201; -.
DR eggNOG; KOG1879; Eukaryota.
DR HOGENOM; CLU_002668_1_0_1; -.
DR InParanoid; D0N7I0; -.
DR OMA; FQTHQLF; -.
DR OrthoDB; 1734at2759; -.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
DR GO; GO:0003980; F:UDP-glucose:glycoprotein glucosyltransferase activity; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR CDD; cd06432; GT8_HUGT1_C_like; 1.
DR InterPro; IPR040497; Glyco_transf_24.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR009448; UDP-g_GGtrans.
DR InterPro; IPR040693; UGGT_TRXL_1.
DR InterPro; IPR040694; UGGT_TRXL_2.
DR InterPro; IPR040692; UGGT_TRXL_3.
DR PANTHER; PTHR11226; UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR11226:SF0; UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE; 1.
DR Pfam; PF18404; Glyco_transf_24; 1.
DR Pfam; PF18400; Thioredoxin_12; 1.
DR Pfam; PF18401; Thioredoxin_13; 1.
DR Pfam; PF18402; Thioredoxin_14; 1.
DR Pfam; PF06427; UDP-g_GGTase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1632
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003012356"
FT DOMAIN 44..233
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18400"
FT DOMAIN 319..444
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18401"
FT DOMAIN 461..744
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18402"
FT DOMAIN 1353..1623
FT /note="Glucosyltransferase 24 catalytic"
FT /evidence="ECO:0000259|Pfam:PF18404"
FT REGION 250..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 588..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..280
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1632 AA; 183755 MW; 6659EC0031469A41 CRC64;
MRPTTWLSAG LAALLTAAQP SLTSARGVHV NLTASWPSSP FFPLMETSEF LAEENPLYFW
QFLEQLEART SYVDLMNSDV DALGTLAVTV AESIAPGSKN VLELMLATRT YSVKVEMFRQ
LGLDSGIRPC GEGADTWAVF YKEKHCVESV ACSEDELDAI LRGKKQQTND QACVAAGVND
VELQVDHKYP YIASDSENAP ISAILYGLVG TEKFHAFHTK LVKQAQINKI QYMGYGVALD
IKNMEYTTID DSKKTDSDDT TSDETGSEEE DEEEEGEIDD EEVDGFLFKP LMARHGAIAN
DLKEFYDILV QKADGEQEQE LKAWHLKDLG ATAVRHIVDA KNPLKRLETL SQDFPVQAKK
LAFSRKSISA KLREEIAVTR MQAANRRVRN KFIMNGIAVD PTERSFNVFD FMKTLKEEWS
VAKQLDSLPL NQSELEDMLK HVRETNQEQP AVRIHVRGAM GGSTPLYLNN IETDPNSASW
SPDVNILRRP AWNLIFVRKN MYECVLVMDP LSGAGRAALS HIGFMRMRGA PVQWALLISS
KELMASNTAE ERQAVVEKYK AFKTTDKASS WHFAKLLMLA QSKDTAEAAA KDETSKSSQG
DDTEVKEEEE RILPTRVASG FLQRVGEDEK SDVLVERLVE AYAEAAGGVG TTEDNEEEAL
ECLKSDQFDS DILAMTEFIH LKHLPLDSFV FNGVVQKDLD IQRSMMASFG RDQPLYVNMA
HRGLLTDDMD LVEELMTEQD AYPAYLSIFE SSEARPGETE VKAPGHLVAD DVDGRLEAAS
RPAVSYLHAP GSRTLPKKQT LIFPVDLNDP RDAGHAYRVV KAVLEDSEQS LRVGVVSQLK
DVEKNSVGEL AAAIIATIGH SDKEAHLKFV LEALNCIVKH KSINTMKDKL RGIWKKTANS
ESDTDPVYEK VLKLLNSKTG KWLTKKQRGV LTQFNTLLRS RFPPAYVESE EDVPKVALPH
LFINGRQVTL PSQSLSDEDM ATIVNFDLKY RTQPVAKALI KRSVTMNAKE ADKLSFAIMK
TTGIVDKYVK TDRTPHMTVD ENSLNTVRLS GDPSLQVAAY VDPLSEAAQV MSSLLRMLHS
QLNATIELVL VPADEYTEFP LQRFYRYLFD KKSSLGATSV EFRKLPVQPI LTMKIDTPEA
WNVQAFHAGD DLDNLRVDPD SPAAVKATTS AVFQLESLLV YGQCRDTTFN MYAPPNGLQL
VLEREVGAQL LHRDTLVMKN LGYFQLQATP GVWSLHLARG RAAELFDIID LETELPLETN
PITVYDFGSH ISQLYVRKKE GKEHEELLQS VEHAAPDKPK SEADETSSTK SYWDAMLKMM
GKHDTKTQDT VEADQVDNDS AVVAQKQRTG ETIHVFSVAS GYLYERFVKI MMSSVLKRTN
NPVTFWLLEN FLSPDFKKSI PVLREQFGMD IRLVTYKWPN WLRQQTEKQR IIWGYKILFL
DVLFPLGVQK IIYVDADQVV RADLKELWEL DLDGKPYGYT PFCDSRNVGF QFWRQGYWKD
HLRGKPYHIS ALYVVDLALF RQMAAGDMLR AVYSHLSADP NSLANLDQDL PNYAQHQIPI
FSLPQEWLWC ESWCSDETKV AAKTIDLCNN PKHKEPKLEM AKRVIAGELF NESWIELDQE
IKEAEAEYAD QA
//
