ID D0N8R8_PHYIT Unreviewed; 837 AA.
AC D0N8R8;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN ORFNames=PITG_07627 {ECO:0000313|EMBL:EEY53953.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY53953.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
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DR EMBL; DS028128; EEY53953.1; -; Genomic_DNA.
DR RefSeq; XP_002904584.1; XM_002904538.1.
DR AlphaFoldDB; D0N8R8; -.
DR STRING; 403677.D0N8R8; -.
DR EnsemblProtists; PITG_07627T0; PITG_07627T0; PITG_07627.
DR GeneID; 9462671; -.
DR KEGG; pif:PITG_07627; -.
DR VEuPathDB; FungiDB:PITG_07627; -.
DR eggNOG; ENOG502S8AD; Eukaryota.
DR HOGENOM; CLU_012148_0_0_1; -.
DR InParanoid; D0N8R8; -.
DR OrthoDB; 12386at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR43102:SF2; GAF DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43102; SLR1143 PROTEIN; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF01590; GAF; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 396..456
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 552..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 837 AA; 93922 MW; BD26BE6F5132FA40 CRC64;
MWATSSMISE SGCSESSRGV RLECDPKQRR LTITGGMDDT DASGLNVQLS DQEIVTDLLA
TLPKLKAAVE DHENRAPNWL RKSKSGEAVE IFELLPTRDG KGDDMDLVHS VVATIEIECH
LNEVLNVLTS HKTNHDLEAS MRAIIPKKKV RQGEVLLQPH ATTLDGAPIR HTRLTQKSTR
GGKTVRFDNT SIPEDEEEDD SERKVLVSVS MTRFKSKRRL DVRGRLRNRH QRLQKLCLAT
LTHQFVGKQR AVHVIKTLPR SVHDQLAPIE EKHQSRSVLG SGLRGLDHIS VGFDIQTRNV
HCIGARGAAQ STKIIAHGYA SVTPPEQFGQ QQQRTMTSYS PSELANYRSS HVNAEAKHVI
ELLTTSLMQF ERVIRRRRLG LQTFIKLKSG DRGSDRQSFQ TCEVCNNRFS LLRREFHCQL
CGHVCCGDCS KQYEVEANVG EVTKKRLCVR CITNVDSCIF EDEDFMVALG PACEYDRRDE
NDTYASIGST VACSEFDSNG SPDDVSSDLY PENVLERSRA LQTLDRLVNS QIKASGKLSL
FERSRLTQSQ LNQSSQLSQS QLSQSHQFSH HQLSQSQSHQ SQFKQSRFKQ AQFDESIVAQ
LRADVEDHLK RTLRATLRDT RRNFAGADES QFSIAPLERD YQLEFDGSQT MSPSHPLPPK
PLPAQERRRL QYVISSGALS PTYDRGALNM LGQIAAANLN CPIGYVTMID QSTQYVVGLH
PRGAIGMSIP REESMCSYTI YHERPLVVKN ALNDIRFSHM GFVIQTGLRF YAGFPIRAPD
SAVVATICAA DYKPHKYISA KQYAEMEALA ELASTLIITP DIEVKTAKRD AHAFPRF
//
