ID D0NB19_PHYIT Unreviewed; 582 AA.
AC D0NB19;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE SubName: Full=Cell 5A endo-1,4-betaglucanase, putative {ECO:0000313|EMBL:EEY55027.1};
GN ORFNames=PITG_08611 {ECO:0000313|EMBL:EEY55027.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY55027.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641, ECO:0000256|RuleBase:RU361153}.
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DR EMBL; DS028130; EEY55027.1; -; Genomic_DNA.
DR RefSeq; XP_002903972.1; XM_002903926.1.
DR AlphaFoldDB; D0NB19; -.
DR STRING; 403677.D0NB19; -.
DR EnsemblProtists; PITG_08611T0; PITG_08611T0; PITG_08611.
DR GeneID; 9462035; -.
DR KEGG; pif:PITG_08611; -.
DR VEuPathDB; FungiDB:PITG_08611; -.
DR eggNOG; ENOG502QUB5; Eukaryota.
DR HOGENOM; CLU_022692_0_0_1; -.
DR InParanoid; D0NB19; -.
DR OMA; PTRESEM; -.
DR OrthoDB; 67431at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR018087; Glyco_hydro_5_CS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR35923:SF2; CELLULASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR35923; MAJOR EXTRACELLULAR ENDOGLUCANASE; 1.
DR Pfam; PF00150; Cellulase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361153};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 83..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 183..518
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 582 AA; 64764 MW; 0F2D1B1E3F1F1B18 CRC64;
MEVSRPVPAA ADDRQATASF SRSSEYSNGN FSGHLDSSQG ARLTEGSVSL GGHRQTEMKI
KATDFDDLPP ETTKDYKGRI RTWPGLLLLL LIVSGAVTVI VLQAKETSDM IHVNQDNYEQ
EQAYKRKIKD GKEDDQVLIS DDGQVGNPKK YPDMGCELPD YQSKNGQIVA VSKNGTEVPV
SIKGVNWFGM ETGLAIPFGL WENMDNGTSV YEVAAFLARN NFNSVRLPLC VKNILNDVAP
EKSLINLNTN RAVNITSYIT TVQSIVEALG YRHITVMISL HTLDTKKSGG AWFSDELGVT
EDEFLSAIDI LTKNLCISKY WNILGLDLKN EPHECSWGGE DPDWQKGATL IGNRMLEDCP
NWMAFVEGIA GSGKITLNGE NRVYFDWWGG GMENAGDFPI TFDVENKLVW SPHYYNTGVS
PAWYLYASGT QGEEGALNGY VELDDETLRN NVEKSMDAMF GYLIERDPNV AMVMGEFAGL
YAKDVHPMLT TKRTTDFTME VMLKAKYAGA YMWSLNPESA YQFNPGDTYG HFTEGLLEDD
WLTPNKVFVD GIAALDAMEN LRMFPCFPQE VEGSDSEEEE EE
//
