ID D0NEX2_PHYIT Unreviewed; 1427 AA.
AC D0NEX2;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Regulator of chromosome condensation (RCC1), putative {ECO:0000313|EMBL:EEY56761.1};
GN ORFNames=PITG_10262 {ECO:0000313|EMBL:EEY56761.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY56761.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS028135; EEY56761.1; -; Genomic_DNA.
DR RefSeq; XP_002902089.1; XM_002902043.1.
DR STRING; 403677.D0NEX2; -.
DR EnsemblProtists; PITG_10262T0; PITG_10262T0; PITG_10262.
DR GeneID; 9473900; -.
DR KEGG; pif:PITG_10262; -.
DR VEuPathDB; FungiDB:PITG_10262; -.
DR eggNOG; KOG0941; Eukaryota.
DR HOGENOM; CLU_001962_0_0_1; -.
DR InParanoid; D0NEX2; -.
DR OMA; KITHATQ; -.
DR OrthoDB; 70365at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR PANTHER; PTHR22870:SF437; X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR-RELATED; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF00415; RCC1; 2.
DR Pfam; PF13540; RCC1_2; 3.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 3.
DR PROSITE; PS00626; RCC1_2; 2.
DR PROSITE; PS50012; RCC1_3; 3.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 41..76
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 77..112
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 129..158
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REPEAT 707..779
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 780..837
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 838..905
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REGION 317..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1025..1045
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1298..1321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1427 AA; 158277 MW; A4D05EA979538549 CRC64;
MIGRKQRKRV VYVDGIPIES TLLEAGESGL KGAEKSDPTS LAALDPQALF DKYDADGSGD
IDFEEFKVLL HELSVNLTEP KAHAYFRRCD RRRRGCISFD ELRLALYTCD PKNPHRTGGF
APGQSLAPRD LFEMFDKDEE GAIDRATFTE LLEFIGRKMP LDKMEELFAT YEDPELEMLS
YLQFKKAWLA VVDVPAELRQ RGEKFNRFLP PKMLAKKLAM LVSLEEKQEA LTLLEANNTL
SDEVIASQRR ELVTEARCLA RVRLAEALDA AGQVYVFGKG AHQRFDCEPK EPDFVDFMDY
DVVRELWQQR VSPAGSNAMA SLSSGVKSIE NKPKNSDNPD KRLSPARTKL EASARAFADR
QVSKATAFLW GKRVNQVACG AAIAYALTDA GEVFCWGGNK RRWKYFYDEA TATNVVEDSD
PGGAALAELA RFGAKRDSSW RKNPLTARSE MLRLFALPSQ VSESHDVHDK LGLRRKYAQV
FEKLVPLTLT DEDRRRRLQL VGQYYGLLSG RSCMRSLDEL METVEPDLDV DNLSLSLFVR
GVEVARPTRT ALLKILGECL ELERECVGEK FHEHMKHQDE IARRHRKERR ERALMAVVDK
ANALWFDLNE LREKMATAER ERLIKGDEEY DKMKRKITHA TQKLKRRARE GHSAVVVPDH
NAEQCQDLLY INGLTARGPV LKFFDGSQAL QSIAVGSRHA LAIHSSGKLY TWGVGSFGRL
GGAQNVECKR DRSNDESEGN PVDSWHSDAH TAQVIPAVRH LRFRAISCGF SHSLALCTDG
TVYAWGSATH GKLGIGPVLV EESFTLAPMA LSSLTSLGVR VRKIACGPSH SALLTVAGAL
YVWGCGDGGR LGLGDDRDIG EDRIPRNGVQ LGVISTPTRV VEPFEHEKVV EVACGAAHTA
VLSAIQRNSG GCVYVAGSNH AVANFTPRFT RVTVPEASTV MAMKVSCGPA HTAFVSTEGE
LYTWGKNIGG STGHDVKLPL LPHPTRVGCM FERPRNLCLD AAVTVTQSSQ NATAIAEFAL
GGDHAAREGQ KKRQSRRSSG QNTAHFAQTQ HEMCPFWQVN LAQHCRIVSI RVVLVSSTSI
DAESARSTAL KYAVMVSEDA FDLEIRGKQA LAKARGHSVH VSLSCDTQNE LKWTAPADTF
GRFVRVQLES VSGASLLSLE RVEVLGASSE QYTGPRVTDV VCAEGMTVAI CTPIGDKEEL
RNMFRRAVRA DRSSLSVLAQ LETFQSCVRE EEQQQQEEEA LYKASQTAKT SIEKREIATA
IAALEAKQRA ETCVLCRPKV PCVICEMEKH VRAAKKKLIT QTPQQPKISV NDRRKQHSQP
STSIALVTAI KRPELALTLE GLCSEFLALD LRSKQDEEEA QQRVELELMD PVALARAKQE
EEAAARLASG QVRANPTRMA RQLFVKFVTS TGFRGHKTQE KRTITTK
//
