ID D0NIA7_PHYIT Unreviewed; 977 AA.
AC D0NIA7;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Transmembrane protein, putative {ECO:0000313|EMBL:EEY59192.1};
GN ORFNames=PITG_11666 {ECO:0000313|EMBL:EEY59192.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY59192.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
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DR EMBL; DS028139; EEY59192.1; -; Genomic_DNA.
DR RefSeq; XP_002901206.1; XM_002901160.1.
DR AlphaFoldDB; D0NIA7; -.
DR EnsemblProtists; PITG_11666T0; PITG_11666T0; PITG_11666.
DR GeneID; 9470726; -.
DR KEGG; pif:PITG_11666; -.
DR VEuPathDB; FungiDB:PITG_11666; -.
DR eggNOG; KOG4177; Eukaryota.
DR HOGENOM; CLU_003933_0_0_1; -.
DR InParanoid; D0NIA7; -.
DR OMA; ARHREHI; -.
DR OrthoDB; 90565at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR24193:SF121; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24193; ANKYRIN REPEAT PROTEIN; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13676; TIR_2; 1.
DR SMART; SM00248; ANK; 8.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:EEY59192.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 321..353
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 391..423
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 529..561
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 562..594
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 703..842
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 43..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 872..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 977 AA; 108567 MW; 7AB7362765021AF3 CRC64;
MVVELSSTDA ETQTLTSQRR RPAIGHGALR EDDSHRTLRS PLLASSGATN RSPTGSIASQ
TLSAGSAPST FLRLRHRHYA NFRELRGKIS RVPRFWLWPR FLYNSFFAKR LILQWLADFK
ASNPEDFEHC RMTVIFSGLI YHMLPVAVLL FLPGSGLRSF EPIPKIRRRL VFQLCELLAV
CALVFDAALV FYFPVVLFTG AIYACDSYAM HLFTVGGAVC YVGLFIVIYY FARYREHIKM
QLGAFTESDQ TEGIRKHDLD LSQDKTMKML SVVRTRLYYA TRRGDLPEMR AILDCAGTRG
LTEFGKLYAS PTIKFKFFAK TRRNPVHVAA YHGNILALEL LKEYGFDMTA QDKYNSVHFS
TGSLFWYFAR IFVKRPSNSL ENMAVSVFQT TLMTPLHCAV STGQTETVRW LLDHGACPNT
LTQASFRSNR VPPLFFAEHA EIARELLIHG ADPLVIPDPG FMNTMTPLQL AYVRGKYAVA
QELEEWGGDV ALTPFHLAAA RNDVLAVRKF LSRKTDIDCL GEMGYVGLNR RTPLHWAAIS
GSTEAVNVLL EAGANPAFQD ARGRSPFHWA ARLNKLDAVR SLIEAGAEPN LADGEFMTPL
MCAALALDGS QELFSELTRA GGDIAYQLPT TGDTALHIAV RGENQSSSLA ALANGGDLMP
HEASALAVLA SGGDLMRMNN EGLRPLDCTA STRLLFELKR AAGQRDVMIS YTHSHLAFAR
KLRQSLEEAN VTTWLDLMDP SGIGGGAVWR EEIARGITNA SVVLCILTED YASSEWCLKE
LALAKQVGTP ILAVSTEGAI VDENLQVYLY TRQIVPFEPA IVGLRRNGGR IEYDYDETRY
RSQFHLLLDG VRDEVEKRRD FTKQNTVASS RTLDLDGDST EGGARSSSRG TMLQTLGNTR
LSPGQFVFFS HGDKHIPLVR KLASQLREAG VACYIDRNVG DQDFNARIQV AQETILRCSG
FVMALAEDKG RPIFPIA
//
