ID D0NNN3_PHYIT Unreviewed; 1468 AA.
AC D0NNN3;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=WW domain-containing protein {ECO:0000259|PROSITE:PS50020};
GN ORFNames=PITG_14108 {ECO:0000313|EMBL:EEY62204.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY62204.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; DS028149; EEY62204.1; -; Genomic_DNA.
DR RefSeq; XP_002899235.1; XM_002899189.1.
DR STRING; 403677.D0NNN3; -.
DR EnsemblProtists; PITG_14108T0; PITG_14108T0; PITG_14108.
DR GeneID; 9468322; -.
DR KEGG; pif:PITG_14108; -.
DR VEuPathDB; FungiDB:PITG_14108; -.
DR eggNOG; KOG0152; Eukaryota.
DR HOGENOM; CLU_250381_0_0_1; -.
DR InParanoid; D0NNN3; -.
DR OMA; RYFGTTW; -.
DR OrthoDB; 622373at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR CDD; cd00201; WW; 2.
DR Gene3D; 1.10.287.2900; -; 1.
DR Gene3D; 1.20.5.190; -; 5.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 3.40.1440.10; GIY-YIG endonuclease; 1.
DR InterPro; IPR012891; GCK_dom.
DR InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR22706:SF1; ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN ISOFORM X1; 1.
DR PANTHER; PTHR22706; UNCHARACTERIZED; 1.
DR Pfam; PF07802; GCK; 1.
DR Pfam; PF00612; IQ; 9.
DR Pfam; PF00397; WW; 1.
DR SMART; SM01227; GCK; 1.
DR SMART; SM00015; IQ; 16.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50096; IQ; 13.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..1468
FT /note="WW domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003012253"
FT DOMAIN 1297..1331
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 1347..1375
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 345..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 480..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1198..1225
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 345..375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..513
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1468 AA; 168856 MW; 3F133B3467C2D46A CRC64;
MSTKFLRTRR LLPFLAAPTA LLSVSSAHLE ASEPEAAPPA QPAVNFVGVF VEKESAARLR
QQFPAKFGSA DEPLVVVLRF QPTEEEQEAF APIFGRAAKL HVKGLAEDDH AQTVLVAVTT
ETGESLEYEG AAEPAHVTLT SAGGLSAGYS SVLLERLRAS DKLRYLLDGD EEINEWTGEL
PAFESKHLPL FSPFPAVEAK IVKVDAKQSE QLALQGTVCL SSRFDVATGE CQAPKAECGF
CKFMKAGPCG KEFTAWETCL DNCKKSGDDF IEKCGAQTLA LRDCVDANPE YYHVLSDGPD
EETEAKHVED DKHTVDSLRA ARFKSVDAAP VSAIWDKAAA SRQLAQSLSA PQRPQQQQNA
SSNQHSVPSI RKTPQVRLRS TKRVSKVPKL SFTKRRGRNA ISNQLSLVGV RQVNAGVYLV
ENVKTGHRYF GTTWDLQNAA AQSFHDLQLG AHPHQALNSS FKQHGEAASG IRFRILEHVR
PPSSPKPSVH TDPVTAKRRR VKRLAAGRDA DSNDDSFDVR AMERKLAARL RFHQRRVVRR
AAYKIVRRFL VIPVLAHAWP IWAKAACVLQ RSMREFVARR KARRRRDGVR RWLAARKLQT
HVRRHLARRL VARMRLDKRR ALAAISVQRT TRGHLARLRV RRLRQRRVDD KAATYIQKMW
RGYSTRTKVT LQRSLGGYLA PHRLHNCPLD ELRDEAARTI QQAYGRWKAR RVREQNEKAT
TIRVAYRNYV ARKFGWAAMT VLSETAMANR IQRIGRRWMF QRGFRCVVTE YRREKAARTI
QCCTRQYQAR TKLYTLRKKK KCAQAIRLIQ SFWRGCRMLL KLRERILKRK RERAARQIQA
TYRAWIARRE YVAIRDMARR NRAATKMQCM FRARQARREL TRRQVVRRLG ACENCRSQLA
TVYHFEAESE LCGVCSDEFA SVGNTVMETL DVAVYRRILV PLVGAQRAYR TFQDKMRLQL
GTCTLCEKKA VRRCCWSCLY GHGVSSNEAK RNGEAALGLT FCRSCDALFH ERKPHERKEI
ERAYAEDAAA VTIQTYYRRF AQRPRREVHR LKHERDSAIV IQRAFRRYQV RRVYNAAAVI
QSTVRGWLAR RVAHALRQER LEKQRNAAAC CIQRHVRGFL ARRRVLHLRQ HNAAVSIQSV
WRGFVARCEL HVLQLEKQRK FCEDLRARLC VVAAQIAESE RVSATRIQTM VRGRQARNEL
LRRKLQAARS AREQLRDRVV ALEVMSAMCI QHHVRERITA PVSRQRLRAQ CCARCFLSRR
TAKRLRLEKQ SAVRIQRAFR YSRAKRRLAR LVDDDTATSA SAWVELFDEA SGYVYYYHTE
TGESVWERPP KMNYSPEDTP RENVGEWVEY WDENVGTSYF YNVKTGEATW TTPAGYQSSN
QEDAAQAWPT TLEEEKQDVE AYGDQYAPYG YEYAEDQAYY GNNGEDYAYP LEQADNELNE
GVDTEYDINY NIYLTQLQQQ QQEDQQQQ
//
