ID D0NUZ0_PHYIT Unreviewed; 557 AA.
AC D0NUZ0;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN ORFNames=PITG_17076 {ECO:0000313|EMBL:EEY66462.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY66462.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
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DR EMBL; DS028167; EEY66462.1; -; Genomic_DNA.
DR RefSeq; XP_002896981.1; XM_002896935.1.
DR AlphaFoldDB; D0NUZ0; -.
DR STRING; 403677.D0NUZ0; -.
DR EnsemblProtists; PITG_17076T0; PITG_17076T0; PITG_17076.
DR GeneID; 9466564; -.
DR KEGG; pif:PITG_17076; -.
DR VEuPathDB; FungiDB:PITG_17076; -.
DR eggNOG; KOG2273; Eukaryota.
DR HOGENOM; CLU_038231_0_0_1; -.
DR InParanoid; D0NUZ0; -.
DR OMA; LHYYEEC; -.
DR OrthoDB; 5475877at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR015404; Vps5_C.
DR PANTHER; PTHR45949; SORTING NEXIN-4; 1.
DR PANTHER; PTHR45949:SF2; SORTING NEXIN-4; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF09325; Vps5; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643}.
FT DOMAIN 143..260
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT COILED 450..477
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 557 AA; 62296 MW; 9BF08A847A0B9B2A CRC64;
MLSLGRSSTS GASGGEFNIA FVNGPIKFHS EEGVLYSRLF HIVDTNADGY IGGTEGAAFI
RRARLMNDAN REIWRLASGG KSQEKLNKDC WFVAMKLVAL VQSTGKCQMQ SLYSGDPLPL
ADFQMEQPVD NVLPEETAPD YERSFVVSVS TPVVVGSGYS RYTQYVISTK TNCSHFPCTT
AQVKRRFSDF EWLQQRLLVH FRGTIIPPLP EKRWTGNMDA TFVEERRQAL EHFINEVCSH
EKLSRTLELQ IVLTASTEGL IAGKELLKVA SIAAAYVPTP ASVSSLWSTL KDGVFMSSNV
QQVEIKTDDD YARIGQHIDE YEKRIREVTR CSDIVYAAQR GEGYEMSRFG SYLSALSEQE
KRDPDMKQLA EVAGDHFETV SNIYQDQLDK LLSMYVSIVR YQAGKVDAVK AVMHNRESAI
HEVQQANASM QRNKERFAAA RASSGAAASA MRAEQKMASA EDRMNHAKEQ VQFIANSLKV
ETKRMDTGKT ANFKTALLSL ANLELDYHVQ SRAAWEGLRS FLELSDEEVA ESRHRAQTSI
TYRKPGEKDL GQIIGLL
//
