ID D0NYL0_PHYIT Unreviewed; 1112 AA.
AC D0NYL0;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PITG_18656 {ECO:0000313|EMBL:EEY68630.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY68630.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
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DR EMBL; DS028188; EEY68630.1; -; Genomic_DNA.
DR RefSeq; XP_002997560.1; XM_002997514.1.
DR AlphaFoldDB; D0NYL0; -.
DR STRING; 403677.D0NYL0; -.
DR EnsemblProtists; PITG_18656T0; PITG_18656T0; PITG_18656.
DR GeneID; 9466368; -.
DR KEGG; pif:PITG_18656; -.
DR VEuPathDB; FungiDB:PITG_18656; -.
DR eggNOG; ENOG502QRT2; Eukaryota.
DR HOGENOM; CLU_010283_0_0_1; -.
DR InParanoid; D0NYL0; -.
DR OMA; VTMMIND; -.
DR OrthoDB; 54712at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13510; FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED; 1.
DR PANTHER; PTHR13510:SF44; RABENOSYN-5; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 445..507
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 1072..1101
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 64..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 547..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 661..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 871..945
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 952..979
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 70..86
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..622
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..679
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1112 AA; 121647 MW; D97182979AB2B742 CRC64;
MLNRGMPRPE YAPFITLPRG ASVPMLGGLA VAGSAPSAVS ALTAAASETL SAALSVAKLN
LHRRRRQTLT DSNAPSSSSS RSNNGRRTPY LDRDDDEEDD PFDPQQQHQE RYHSQPRPRK
STRSPSSSRS PAPSPSRDSA SSTRSGGFAS MTSLSNRSPS ARSSSVTSPS SLRDESMSSM
VSDMAQNLPE LSTERLQALV NFIDKSVDDA YNLSLGFGRV RWTPSRAREG VTIHRARSGP
DNTLLDAAVR GKCNVSATFR EITDLLITET SADFADHESA VNPSEFLDGQ VLYTLVPRTP
EERFVCVKWH CVRSLAPSVA KHRDYVYVEL VDSFEDGDGR RVGYRLCKSV ELDVLPPRDT
KHLFVRAKTL TLQTWSERAP GSLEFVTMVI NDLGDRLPSW LVHKMVDTAA MRSACIRDHI
NQRRLDMLVY AGPRDMVPLS RRVCCVVCTR SFSLVRKKYN CAACGDVICN QCSIQELVTA
HQRLSDLSAP GGKRKTRICV KCSSKMQSRE LPRRASSARQ SDTSRVSSDG SIRSSLASNS
SFLARSHASA GKTSDETRRS FLSDSTTGTS SQDSAEEGNR GSGNGSSGIR KQVPNMFQFR
PTSSSMGKSE RLSKASTSPS SPGEDEDRLD VEELQPQLLG DSILAPPAPV ELDLGIGKYK
ETFTQQPTRP ERDYEAEAAE LAEYSDEEEE YAEDDAGNFL NTEGHTHDAV RQSLSQARVM
TLEVDGPTVL KVEVASFLTE EENASLDTMS NDSDSASFLT VDENSKIVES RFSGKLENVP
IPVQVEELTV EEIMPENVRT VPRRSLDLEE VEVEELVIEE IHPVNVGIVP RRSEEFAVEE
IQLENSSRLS METEEVEMPV VVHMVAKKLV VGSGGRRGRD SRRAPAPQPS SAPPPPPKVA
DMLTSSMTNV SATKKARAAP PPTPTTAPES TQMPTQAPAP EPEEETLKLE DLQVHLNRMD
QISASLRDLR KEMKSTTAAP ASTQTAMAAL TSFESKANAE RAAKIAANFI SLLDRNAAPA
ARRAQQHLKQ HGGPRTSLFN LTLAMGDGTF VDYLVDSTFE DVGESPDGTG IGWQAVVSQT
TGKQYFFNQN CALASWTLPG PDVYRGMVYM VL
//
