ID D0NZQ9_PHYIT Unreviewed; 687 AA.
AC D0NZQ9;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Nonsense transcript regulator {ECO:0000313|EMBL:EEY69624.1};
GN ORFNames=PITG_18912 {ECO:0000313|EMBL:EEY69624.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY69624.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
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DR EMBL; DS028203; EEY69624.1; -; Genomic_DNA.
DR RefSeq; XP_002997185.1; XM_002997139.1.
DR AlphaFoldDB; D0NZQ9; -.
DR STRING; 403677.D0NZQ9; -.
DR EnsemblProtists; PITG_18912T0; PITG_18912T0; PITG_18912.
DR GeneID; 9473638; -.
DR KEGG; pif:PITG_18912; -.
DR VEuPathDB; FungiDB:PITG_18912; -.
DR eggNOG; KOG1802; Eukaryota.
DR HOGENOM; CLU_001666_4_3_1; -.
DR InParanoid; D0NZQ9; -.
DR OMA; YANDITF; -.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR CDD; cd18039; DEXXQc_UPF1; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 6.10.140.1240; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF364; REGULATOR OF NONSENSE TRANSCRIPTS 1; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006643}.
FT DOMAIN 102..199
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 205..305
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 313..511
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 538..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..678
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 687 AA; 76099 MW; F01846892EB6BD33 CRC64;
MLYGKDWEGT GHVLRLEESE VALEMRSSNV PIEITDGYLV DFVWKSTSFD RMQAAMKTFA
VDDTSLTGYL YHKILGHDVG VQALRIPRSV GTHFSAPGLP ELNTFQMEAV KGVLEQPLSL
IQGPPGTGKT VTSASIVFHM SKQNMGQVLV TAPSNIAVDH LTMKISATGL RVVRLAAKSR
EAVASSVEHL SLHAMIKSLD SPDKADLRKL MQLKDDIGEL SSQDEKRFKS LKRQAEREIL
QAADVICTTC VGAGDPRLSN FRFRQVLIDE ATQATEPECL IPIVQGAKHV VMVGDHRQLG
PVVMNKKAAK AGLNNSLFDR LVKSDTKHRP FRLRVQYRMH PFLSEFPSNE FYEGDLQNGV
AASERQLSSV DFPWPNPNKP TFFYICLGAE EISSSGTSYL NRTEASNVEK IVTTFLKAGV
LPSQIGVITP YEGQRAYVVS YMQRNGPLRS QLYKDVEVAS VDSFQGREKD LIILSCVRSN
ENQGIGFLSD ERRLNVALTR AKYGVILLGN PRVLAKQTLW NKLLNHYRDN QLIMEGPLNN
LTPSHMQFPV QRHSERGARR EGNGFNRRGP APPLDSRFDP RYEQTGGLPL DPLAAGGLPP
PAPQRGPRRG PSSYVPGSMG PLTQDGMTQS SMGMDGPFTQ MAQTQSFSQL SSDKFAMSQD
SFGYEHDFKS QNMPMSQDAR APGSDFY
//
