ID D0P2H6_PHYIT Unreviewed; 854 AA.
AC D0P2H6;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=AMP-binding enzyme, putative {ECO:0000313|EMBL:EEY56270.1};
GN ORFNames=PITG_20656 {ECO:0000313|EMBL:EEY56270.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY56270.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
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DR EMBL; DS028292; EEY56270.1; -; Genomic_DNA.
DR RefSeq; XP_002895493.1; XM_002895447.1.
DR AlphaFoldDB; D0P2H6; -.
DR STRING; 403677.D0P2H6; -.
DR EnsemblProtists; PITG_20656T0; PITG_20656T0; PITG_20656.
DR GeneID; 9480141; -.
DR KEGG; pif:PITG_20656; -.
DR VEuPathDB; FungiDB:PITG_20656; -.
DR eggNOG; KOG1178; Eukaryota.
DR HOGENOM; CLU_000022_2_4_1; -.
DR InParanoid; D0P2H6; -.
DR OMA; RTANCAC; -.
DR OrthoDB; 2301216at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..854
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003013788"
FT DOMAIN 729..813
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 854 AA; 95897 MW; B304516FEB227E25 CRC64;
MGLLAVFYLL VERLSGQQDF VIGAPSSGQD AAELQDIMGY FVNTLPLRLG GKFAGDEDFK
SFLKNVRKVV LGAYNNMEIP FHKVLEHLRA SAHSNDDIER RWQHPLFQVM FSWEQSEDTS
STTYTELELP HQSAKFDLML SMRYRRLNGD ECLLAQVWKT PDHPALHFEG TQWTYQDLWK
YSCRVTRALC MLDISGCSAE LHIGLLLDRG VENVAAMIGI LRLGAVFVPL DPEFPRERLR
YMTRDSELQV IITQRKHAEI AAFVSSRESE EELAPRVLNY EDVDRLTSSS DGCARDDEFD
SESRLLKRQK RDSDTATAYV LYTSGSTGNP KGVVVPHAAL MTTLWWTVRT YEVTSSDVFL
QSTSTTLDGS LSQLFSPLLV GGSARITRPK GLHDLQYMRK VLLEAPHISF CVFVPSYFSL
IVDYMSENGD TFPASIKHVI LAGEAFPIEL ARQFYKKHPA CSTCLVNEYG PTEASITSTA
FRMPRELAMQ NESSLFQGLH SVPIGKPIDE HPVVVLDAQR RLVPVNVPGE LYIGGAGVAR
GYWRRPELTE NSFVLHKKLE EIASLAQKRT RRWYKTGDLV KWLPSGELVF LGRTDAQVKL
HGMRGELQEV RNILLRSSSI KAAEVLSVPQ LTSPGQKQRQ MSSTLVAFVM PAESIDELSV
RDGYLTELRA YLDQHLPLHM VPQSIQVVSS WPRTPNGKID LRTLASWAGS NSTDSRPGEQ
KKESTITVQL ATDILRQVWM QALELQPVDG DQDMDDKLEA NLMSKSFFEL GGDSLAAIRA
IALAQARGLS LALEQFFRTS SLPEMARRAA ASMVDLRQWT SETLVPPNWP TAKNTRTVFL
VFMTLTGLSG TCWN
//
