ID D0SAA3_ACIJO Unreviewed; 787 AA.
AC D0SAA3;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=DNA internalization competence protein ComEC/Rec2-like protein {ECO:0000313|EMBL:EEY97340.1};
DE Flags: Fragment;
GN ORFNames=HMPREF0016_00423 {ECO:0000313|EMBL:EEY97340.1};
OS Acinetobacter johnsonii SH046.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=575586 {ECO:0000313|EMBL:EEY97340.1, ECO:0000313|Proteomes:UP000012047};
RN [1] {ECO:0000313|Proteomes:UP000012047}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH046 {ECO:0000313|Proteomes:UP000012047};
RX PubMed=23144699; DOI=10.1371/journal.pone.0046984;
RA Peleg A.Y., de Breij A., Adams M.D., Cerqueira G.M., Mocali S.,
RA Galardini M., Nibbering P.H., Earl A.M., Ward D.V., Paterson D.L.,
RA Seifert H., Dijkshoorn L.;
RT "The success of Acinetobacter species; genetic, metabolic and virulence
RT attributes.";
RL PLoS ONE 7:E46984-E46984(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GG704964; EEY97340.1; -; Genomic_DNA.
DR AlphaFoldDB; D0SAA3; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR HOGENOM; CLU_010363_3_1_6; -.
DR Proteomes; UP000012047; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 238..519
FT /note="ComEC/Rec2-related protein"
FT /evidence="ECO:0000259|Pfam:PF03772"
FT DOMAIN 551..629
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|Pfam:PF00753"
FT NON_TER 787
FT /evidence="ECO:0000313|EMBL:EEY97340.1"
SQ SEQUENCE 787 AA; 89783 MW; C638BBB8BBFBDE4B CRC64;
MKFLYAAAWI VGIALMGQTV PILNHLFYPA LILVILLLPL QLFLFKHKHA LILQFICGLI
YSMLFLTAGY HYAQSALQQR LAYKEKKVED AEVIVYIAKI NQLGADTIQQ EIQVLNRHVQ
PVQWLSFQKR ISDEQAVLEL GKYYRLTGEI RPAHSYAVQG VFDVEQWYLQ RNLMSGFKLK
HIHPLSESEI SALGYTYYLR KQQGVLNKIQ LGIEQQRLNI RHFIYSQPLS HKGLILALLT
GDESFLDKET TALFQRFGIS HLLAISGPHV LIFAVMLCWL LQKVLNRYWP QIFLKIPRPY
ALLLPFCCCV LLYCAFVGFE IPALRTLLSC FCLSVLIWLR QKISALTLLL LSASLLLLFD
PFSILSAAFW LSYGACFVLL RIYQTTIRLD LTRPQSWQKK FVFSLKLLVE SQWKIFVALM
PLVIIFFKQV SWVSPISNLV AIPLISLLVV PLEVLAALTF YLFEPLSSLL FQLADWVLVF
LLGILNVLDA LLPIKLYPIA LNTWQVILLI LLLIIVFMPK PSLPKSWLVL GLIPLLGFSS
QNRPFELIVL DVGQGQAVYM QHGQQYTMID VGGSYDESKF SVAKQIIQPF LSKQGVSQLD
QLILTHLDQD HSGSYATLKN ELSINQIYSN QQLDVANRSN FNYCQQGQIW HWSEQVEIKI
LSPKANQLAQ VPYQQNELSC VVYIRVKDVQ PYQYFLIMGD AGWQTEFQLL QYYPDLKVDV
LVLGHHGSRH SSAYAFLKHY QPKLAIASAG FNNRYGHPST VTQARLKALN IPLLTTAGQG
SIGFIAQ
//
