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Entry: D0YW13_PHODD
LinkDB: D0YW13_PHODD
Original site: D0YW13_PHODD 
ID   D0YW13_PHODD            Unreviewed;       355 AA.
AC   D0YW13;
DT   19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2010, sequence version 1.
DT   08-MAY-2019, entry version 43.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=VDA_001318 {ECO:0000313|EMBL:EEZ40293.1};
OS   Photobacterium damselae subsp. damselae CIP 102761.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Photobacterium.
OX   NCBI_TaxID=675817 {ECO:0000313|EMBL:EEZ40293.1, ECO:0000313|Proteomes:UP000003579};
RN   [1] {ECO:0000313|EMBL:EEZ40293.1, ECO:0000313|Proteomes:UP000003579}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIP 102761 {ECO:0000313|EMBL:EEZ40293.1,
RC   ECO:0000313|Proteomes:UP000003579};
RG   Los Alamos National Laboratory (LANL);
RG   National Microbial Pathogen Data Resource (NMPDR);
RA   Munk A.C., Tapia R., Green L., Rogers Y., Detter J.C., Bruce D.,
RA   Brettin T.S., Colwell R., Huq A., Grim C.J., Hasan N.A., Vonstein V.,
RA   Bartels D.;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; ADBS01000001; EEZ40293.1; -; Genomic_DNA.
DR   RefSeq; WP_005297854.1; NZ_ADBS01000001.1.
DR   STRING; 675817.VDA_001318; -.
DR   EnsemblBacteria; EEZ40293; EEZ40293; VDA_001318.
DR   GeneID; 34511764; -.
DR   eggNOG; ENOG4105E99; Bacteria.
DR   eggNOG; COG0722; LUCA.
DR   OrthoDB; 853329at2; -.
DR   BioCyc; PDAM675817:G11UI-180-MONOMER; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000003579; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000003579};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003579};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:EEZ40293.1}.
FT   DOMAIN       41    340       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   355 AA;  39084 MW;  2DBA6CE3C9A9010B CRC64;
     MHKDQLNNIH IQDESVLITP TQLKSKLPVS ASALSFIQQS RQTIANIIHK KDHRLLVVCG
     PCSIHDVEAA KEYGKKLKAL AEELSDQLYI VMRVYFEKPR TTVGWKGLIN DPYLDGSFEV
     EEGLHIARQL LIDLVEMGIP LATEALDPIS PQYLGDLFSW AAIGARTTES QTHREMASGL
     SLPVGFKNGT DGSLATAINA MEAAASGHKF MGINPDGQVA LLSTQGNPDG HIILRGGKQT
     NYDSVSVTEC EQEMIASGLS PSLMVDCSHA NSRKDFRRQP LVAEDVIHQI REGNRSIIGL
     MIESHLQEGN QSADLPRADM VYGQSITDAC IGWQTTEQLL RHAKQELVPF LQNRI
//
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