ID D1A4X8_THECD Unreviewed; 501 AA.
AC D1A4X8;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=GntR domain protein {ECO:0000313|EMBL:ACY98147.1};
GN OrderedLocusNames=Tcur_2591 {ECO:0000313|EMBL:ACY98147.1};
OS Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC
OS 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=471852 {ECO:0000313|EMBL:ACY98147.1, ECO:0000313|Proteomes:UP000001918};
RN [1] {ECO:0000313|EMBL:ACY98147.1, ECO:0000313|Proteomes:UP000001918}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 /
RC NCIMB 10081 / Henssen B9 {ECO:0000313|Proteomes:UP000001918};
RX PubMed=21475583; DOI=10.4056/sigs.1453580;
RA Chertkov O., Sikorski J., Nolan M., Lapidus A., Lucas S., Del Rio T.G.,
RA Tice H., Cheng J.F., Goodwin L., Pitluck S., Liolios K., Ivanova N.,
RA Mavromatis K., Mikhailova N., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Djao O.D., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Brettin T., Han C., Detter J.C., Rohde M., Goker M., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Thermomonospora curvata type strain (B9).";
RL Stand. Genomic Sci. 1:13-22(2011).
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DR EMBL; CP001738; ACY98147.1; -; Genomic_DNA.
DR AlphaFoldDB; D1A4X8; -.
DR STRING; 471852.Tcur_2591; -.
DR KEGG; tcu:Tcur_2591; -.
DR eggNOG; COG2186; Bacteria.
DR HOGENOM; CLU_564773_0_0_11; -.
DR Proteomes; UP000001918; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR011711; GntR_C.
DR InterPro; IPR008920; TF_FadR/GntR_C.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43537:SF5; GALACTONATE OPERON TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR Pfam; PF07729; FCD; 2.
DR Pfam; PF00392; GntR; 2.
DR SMART; SM00895; FCD; 2.
DR SMART; SM00345; HTH_GNTR; 2.
DR SUPFAM; SSF48008; GntR ligand-binding domain-like; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS50949; HTH_GNTR; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001918};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 34..104
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT DOMAIN 280..349
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 501 AA; 54992 MW; 7A0C5E711550DDE8 CRC64;
MARADVNAPV ADMEEPAAVR GPGGRRHPDG APAGKLAAQI ARRIEDDIIR LGWPVGRNLG
SEAELRERYQ VSRSVLREAV RLVEHHRVAR MRRGPGGGLL VTAPDAGPAG HAMVIYLDYV
GTSVDDLMDA RLLLEPPAAA LAAERLTEDG IERLRRVLRE EEERPEEPGA WPRDRLHTLL
GELSGNPALH LFIDVLTRLT ARYAHHSRRI SNAEAARAKA GSRHEHARLV DAVVSGDAGL
AQAHLTEHLH QIADWLHRHR APEGAPAVPA EPRPPGGPGA KLAEVIAARI HDQIAAAGWP
VGQVLGSETD LLVRYGISRA VLREAVRLLE HHRVARMRRG PGGGLVVTVP EPDAGIDTMA
LYLDYQGVTG EDLRVVRDAI ELGTLRRVTA RHRDPQVAER LHAALERTAE WLGPGRAGAD
LFHTELAELS GNPVLVMFLR TLTELWARHT AAQEQPPPGL EAAAEVERVH RRILEAILDG
DQSMAQYRMR RHLKALTAWY H
//
