ID   D1A840_THECD            Unreviewed;       247 AA.
AC   D1A840;
DT   19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2010, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Type II secretion system protein {ECO:0000313|EMBL:ACZ00355.1};
GN   OrderedLocusNames=Tcur_4837 {ECO:0000313|EMBL:ACZ00355.1};
OS   Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC
OS   9072 / NBRC 15933 / NCIMB 10081 / Henssen B9).
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Thermomonospora.
OX   NCBI_TaxID=471852 {ECO:0000313|EMBL:ACZ00355.1, ECO:0000313|Proteomes:UP000001918};
RN   [1] {ECO:0000313|EMBL:ACZ00355.1, ECO:0000313|Proteomes:UP000001918}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 /
RC   NCIMB 10081 / Henssen B9 {ECO:0000313|Proteomes:UP000001918};
RX   PubMed=21475583; DOI=10.4056/sigs.1453580;
RA   Chertkov O., Sikorski J., Nolan M., Lapidus A., Lucas S., Del Rio T.G.,
RA   Tice H., Cheng J.F., Goodwin L., Pitluck S., Liolios K., Ivanova N.,
RA   Mavromatis K., Mikhailova N., Ovchinnikova G., Pati A., Chen A.,
RA   Palaniappan K., Djao O.D., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Brettin T., Han C., Detter J.C., Rohde M., Goker M., Woyke T., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT   "Complete genome sequence of Thermomonospora curvata type strain (B9).";
RL   Stand. Genomic Sci. 1:13-22(2011).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP001738; ACZ00355.1; -; Genomic_DNA.
DR   RefSeq; WP_012855136.1; NC_013510.1.
DR   AlphaFoldDB; D1A840; -.
DR   STRING; 471852.Tcur_4837; -.
DR   KEGG; tcu:Tcur_4837; -.
DR   eggNOG; COG4965; Bacteria.
DR   HOGENOM; CLU_065779_4_0_11; -.
DR   Proteomes; UP000001918; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR018076; T2SS_GspF_dom.
DR   PANTHER; PTHR35007:SF4; CONSERVED TRANSMEMBRANE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR35007; INTEGRAL MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF00482; T2SSF; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001918};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..247
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039580618"
FT   TRANSMEM        216..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          122..200
FT                   /note="Type II secretion system protein GspF"
FT                   /evidence="ECO:0000259|Pfam:PF00482"
SQ   SEQUENCE   247 AA;  25146 MW;  7816D19D2C3087BE CRC64;
     MSAAGMAVIC AALAAWVGLS PSAAADRLAG LAGTPRHSPG PALLRRVRAL AAAVREKHRA
     VRLWRGAIIE LCDGVAAELH AGRTPEAAFT AAAAVLPAEV SVPLLAERRR GGPAGPPDPG
     DIPAALERLS ARPGAEGLRL LGACWRIGAD SGATFATVIA DLAAALRDEE AQRREVAAQL
     AGPRATARLL AGLPLLGLGM AAALGADPLA FLCGTLPGLI CLTLGLGLDV LGLWWTNRLA
     RSAEAMR
//