ID D1AB42_THECD Unreviewed; 280 AA.
AC D1AB42;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Aldo/keto reductase {ECO:0000313|EMBL:ACY98985.1};
GN OrderedLocusNames=Tcur_3447 {ECO:0000313|EMBL:ACY98985.1};
OS Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC
OS 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=471852 {ECO:0000313|EMBL:ACY98985.1, ECO:0000313|Proteomes:UP000001918};
RN [1] {ECO:0000313|EMBL:ACY98985.1, ECO:0000313|Proteomes:UP000001918}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 /
RC NCIMB 10081 / Henssen B9 {ECO:0000313|Proteomes:UP000001918};
RX PubMed=21475583; DOI=10.4056/sigs.1453580;
RA Chertkov O., Sikorski J., Nolan M., Lapidus A., Lucas S., Del Rio T.G.,
RA Tice H., Cheng J.F., Goodwin L., Pitluck S., Liolios K., Ivanova N.,
RA Mavromatis K., Mikhailova N., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Djao O.D., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Brettin T., Han C., Detter J.C., Rohde M., Goker M., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Thermomonospora curvata type strain (B9).";
RL Stand. Genomic Sci. 1:13-22(2011).
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DR EMBL; CP001738; ACY98985.1; -; Genomic_DNA.
DR AlphaFoldDB; D1AB42; -.
DR STRING; 471852.Tcur_3447; -.
DR KEGG; tcu:Tcur_3447; -.
DR eggNOG; COG0667; Bacteria.
DR HOGENOM; CLU_023205_2_1_11; -.
DR OrthoDB; 9768793at2; -.
DR Proteomes; UP000001918; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd19088; AKR_AKR13B1; 1.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR020471; AKR.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43625; AFLATOXIN B1 ALDEHYDE REDUCTASE; 1.
DR PANTHER; PTHR43625:SF40; ALDO-KETO REDUCTASE YAKC [NADP(+)]; 1.
DR Pfam; PF00248; Aldo_ket_red; 2.
DR PRINTS; PR00069; ALDKETRDTASE.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001918}.
FT DOMAIN 16..213
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
FT DOMAIN 219..278
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
SQ SEQUENCE 280 AA; 30013 MW; 2939A49A6C29CA20 CRC64;
MRNEHWNLGG DLQITRMGFG AMRLPAKSWD GPAGDRDTAL AVLRRAVELG VTHIDTAAFY
TYGDLAANEL IRQALHPYPE GLVIATKVGP RLDERGRPSG EQTAGELRAS VERNLRELGV
DRLDLVYLRV GGLGGPPAGS IADRFAALAA LRDEGLIRHL GVSNVSAAHL AEARAIAPVA
AVQNRYALTA REDDPLVDEC TRAGIAYVPF FPLWGLPDER AAKVAARHGA TAAQIMLAWL
LARSPAILAI PGTSSLRHLE ENMAATRIRL TAEDLAELGG
//
