ID D1AE76_THECD Unreviewed; 214 AA.
AC D1AE76;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Zn-dependent hydrolase of the beta-lactamase fold-like protein {ECO:0000313|EMBL:ACY99502.1};
GN OrderedLocusNames=Tcur_3973 {ECO:0000313|EMBL:ACY99502.1};
OS Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC
OS 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=471852 {ECO:0000313|EMBL:ACY99502.1, ECO:0000313|Proteomes:UP000001918};
RN [1] {ECO:0000313|EMBL:ACY99502.1, ECO:0000313|Proteomes:UP000001918}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 /
RC NCIMB 10081 / Henssen B9 {ECO:0000313|Proteomes:UP000001918};
RX PubMed=21475583; DOI=10.4056/sigs.1453580;
RA Chertkov O., Sikorski J., Nolan M., Lapidus A., Lucas S., Del Rio T.G.,
RA Tice H., Cheng J.F., Goodwin L., Pitluck S., Liolios K., Ivanova N.,
RA Mavromatis K., Mikhailova N., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Djao O.D., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Brettin T., Han C., Detter J.C., Rohde M., Goker M., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Thermomonospora curvata type strain (B9).";
RL Stand. Genomic Sci. 1:13-22(2011).
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DR EMBL; CP001738; ACY99502.1; -; Genomic_DNA.
DR RefSeq; WP_012854286.1; NC_013510.1.
DR AlphaFoldDB; D1AE76; -.
DR STRING; 471852.Tcur_3973; -.
DR KEGG; tcu:Tcur_3973; -.
DR eggNOG; COG2220; Bacteria.
DR HOGENOM; CLU_091682_0_0_11; -.
DR OrthoDB; 3190691at2; -.
DR Proteomes; UP000001918; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR43546:SF3; UPF0173 METAL-DEPENDENT HYDROLASE MJ1163; 1.
DR PANTHER; PTHR43546; UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED; 1.
DR Pfam; PF13483; Lactamase_B_3; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ACY99502.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001918}.
FT DOMAIN 7..175
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 214 AA; 23291 MW; 48816FA864F2349F CRC64;
MRLTKLGHSC VRLSKDEGTL VIDPGGLTPE QDALEGADAV LITHEHFDHF DEDRLRQAMA
ANERLRVYAS RVVASKLADL GERVKSVGHG DALTVAGFDI HVYGEDHEIL DPDVPPIPNT
GYLIDGQVFH PGDALTVPPE PVPTLCLPGS APWMKVSEMY SYVKEIAPER AYVIHDGILN
DVGIAVMENH VSNAAAKAGK DYRRLKPGES VELP
//
