ID   D1BBJ5_SANKS            Unreviewed;       374 AA.
AC   D1BBJ5;
DT   19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2010, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   SubName: Full=IMP dehydrogenase family protein {ECO:0000313|EMBL:ACZ22766.1};
GN   OrderedLocusNames=Sked_28640 {ECO:0000313|EMBL:ACZ22766.1};
OS   Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74).
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Sanguibacteraceae;
OC   Sanguibacter.
OX   NCBI_TaxID=446469 {ECO:0000313|EMBL:ACZ22766.1, ECO:0000313|Proteomes:UP000000322};
RN   [1] {ECO:0000313|EMBL:ACZ22766.1, ECO:0000313|Proteomes:UP000000322}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74
RC   {ECO:0000313|Proteomes:UP000000322};
RX   PubMed=21304646;
RA   Ivanova N., Sikorski J., Sims D., Brettin T., Detter J.C., Han C.,
RA   Lapidus A., Copeland A., Glavina Del Rio T., Nolan M., Chen F., Lucas S.,
RA   Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Pati A.,
RA   Mavromatis K., Chen A., Palaniappan K., D'haeseleer P., Chain P.,
RA   Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Goker M., Pukall R.,
RA   Klenk H.P., Kyrpides N.C.;
RT   "Complete genome sequence of Sanguibacter keddieii type strain (ST-74).";
RL   Stand. Genomic Sci. 1:110-118(2009).
CC   -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC       {ECO:0000256|ARBA:ARBA00005502}.
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DR   EMBL; CP001819; ACZ22766.1; -; Genomic_DNA.
DR   RefSeq; WP_012867835.1; NC_013521.1.
DR   AlphaFoldDB; D1BBJ5; -.
DR   STRING; 446469.Sked_28640; -.
DR   KEGG; ske:Sked_28640; -.
DR   eggNOG; COG0516; Bacteria.
DR   HOGENOM; CLU_064068_0_0_11; -.
DR   OrthoDB; 9805398at2; -.
DR   Proteomes; UP000000322; Chromosome.
DR   GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR   CDD; cd00381; IMPDH; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR005990; IMP_DH.
DR   InterPro; IPR005992; IMP_DH-rel2.
DR   InterPro; IPR001093; IMP_DH_GMPRt.
DR   NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR   PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR   Pfam; PF00478; IMPDH; 1.
DR   SMART; SM01240; IMPDH; 1.
DR   SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE   3: Inferred from homology;
FT   DOMAIN          16..298
FT                   /note="IMP dehydrogenase/GMP reductase"
FT                   /evidence="ECO:0000259|Pfam:PF00478"
SQ   SEQUENCE   374 AA;  39634 MW;  68E2F340788630A0 CRC64;
     MSNEIEIGRG KRGRRAFSFD DIAVVPSRRT RDPEDVSVGW QIDAYHFDLP IVAAPMDSVM
     SPATAVALGQ HGGLGVLDLE GLWTRYEDPT ALLAEIAQLE PEQATRRMQE IYAAPIQPEL
     ITQRLKEIRA AGVTVAGALS PQRTQEFYQT VIDAGVDLFV IRGTTVSAEH VSGNAEPLNL
     KRFIYELDVP VIVGGASTYT AALHLMRTGA AGVLVGFGGG AAHTTRVSLG IHAPMATAVA
     DVAAARRDYL DESGGRYVHV IADGGVGRAG DLVKAVACGA DAVMVGAALA RAEEAPGQGW
     HWGSEAHHPQ LPRGERVSVG TAGSLAEILF GPGRQADGTL NLVGALKRAM ATTGYSDLKE
     FQRVEVVVSP YQPR
//