ID   D1BD48_SANKS            Unreviewed;       704 AA.
AC   D1BD48;
DT   19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2010, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   RecName: Full=alpha-galactosidase {ECO:0000256|ARBA:ARBA00012755};
DE            EC=3.2.1.22 {ECO:0000256|ARBA:ARBA00012755};
GN   OrderedLocusNames=Sked_31550 {ECO:0000313|EMBL:ACZ23052.1};
OS   Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74).
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Sanguibacteraceae;
OC   Sanguibacter.
OX   NCBI_TaxID=446469 {ECO:0000313|EMBL:ACZ23052.1, ECO:0000313|Proteomes:UP000000322};
RN   [1] {ECO:0000313|EMBL:ACZ23052.1, ECO:0000313|Proteomes:UP000000322}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74
RC   {ECO:0000313|Proteomes:UP000000322};
RX   PubMed=21304646;
RA   Ivanova N., Sikorski J., Sims D., Brettin T., Detter J.C., Han C.,
RA   Lapidus A., Copeland A., Glavina Del Rio T., Nolan M., Chen F., Lucas S.,
RA   Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Pati A.,
RA   Mavromatis K., Chen A., Palaniappan K., D'haeseleer P., Chain P.,
RA   Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Goker M., Pukall R.,
RA   Klenk H.P., Kyrpides N.C.;
RT   "Complete genome sequence of Sanguibacter keddieii type strain (ST-74).";
RL   Stand. Genomic Sci. 1:110-118(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal, non-reducing alpha-D-galactose
CC         residues in alpha-D-galactosides, including galactose
CC         oligosaccharides, galactomannans and galactolipids.; EC=3.2.1.22;
CC         Evidence={ECO:0000256|ARBA:ARBA00001255};
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DR   EMBL; CP001819; ACZ23052.1; -; Genomic_DNA.
DR   AlphaFoldDB; D1BD48; -.
DR   STRING; 446469.Sked_31550; -.
DR   CAZy; GH36; Glycoside Hydrolase Family 36.
DR   KEGG; ske:Sked_31550; -.
DR   eggNOG; COG3345; Bacteria.
DR   HOGENOM; CLU_009640_3_1_11; -.
DR   Proteomes; UP000000322; Chromosome.
DR   GO; GO:0004557; F:alpha-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR   CDD; cd14791; GH36; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 2.70.98.60; alpha-galactosidase from lactobacil brevis; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR038417; Alpga-gal_N_sf.
DR   InterPro; IPR000111; Glyco_hydro_27/36_CS.
DR   InterPro; IPR002252; Glyco_hydro_36.
DR   InterPro; IPR031705; Glyco_hydro_36_C.
DR   InterPro; IPR031704; Glyco_hydro_36_N.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR43053:SF3; ALPHA-GALACTOSIDASE C-RELATED; 1.
DR   PANTHER; PTHR43053; GLYCOSIDASE FAMILY 31; 1.
DR   Pfam; PF16874; Glyco_hydro_36C; 1.
DR   Pfam; PF16875; Glyco_hydro_36N; 1.
DR   Pfam; PF02065; Melibiase; 1.
DR   PRINTS; PR00743; GLHYDRLASE36.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS00512; ALPHA_GALACTOSIDASE; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          19..249
FT                   /note="Glycosyl hydrolase family 36 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16875"
FT   DOMAIN          610..688
FT                   /note="Glycosyl hydrolase family 36 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16874"
SQ   SEQUENCE   704 AA;  75741 MW;  3E84B7BCA62E73A8 CRC64;
     MIHLRNGGTS LVIDPTTPGL PTIVHWGHDL GDAAQADLDG LALAAEPQRV SGGLDVPARL
     TLLPLDAAGW LGTPGLEGHR SGRVFSPSFA LSTVEHGPST ATITAVDDHG ALTLVVELEV
     SDAGLVRQRL SLTNTGPDDY SLLALAATFP LPAQATEIMD TTGRHLRERS PQRRALTVGT
     HLRESRKGRP GADATLLLAA GTPGFGFERG QVHAVHVAWS GNHRLAAERT VTAESALTAG
     ELLAPGEVDL APGATYSTPW VLGSWGDGLT ELSARFHTEL RSRPRHPQRP RPVTLNTWEA
     VYFDHDLATL TALAERAAAV GVERFVLDDG WFLGRRDDTA GLGDWTVDPA VWPHGLTPLV
     ETVTGLGMEF GLWVEPEMVN LDSDLARAHP GWILQPGGRL PVEGRQQHVL NLADPDAYAH
     VFESLDALLV EHPISYLKWD HNRELTSAGD ARTGRATVHE HTLALYRLLD ELHARHPALE
     IESCASGGAR VDLGILERTD RVWTSDCIDP LERLDNQRYT GLLVPPELLG AHVGGPRSHS
     THRTHDLDLR AGVAFFGHLG IEWDLTTVDD DQLAALGRWV EAHKQARDLL HTGRVVHADL
     PVATADLRGV VAQDRSRALY AYTQTATSLT YPAGRVHLPG LDPDASYRVR LAAPTAALAG
     PGQSPLRWAS DGARSTGRAL GTTGIQAPVL YPEELVLLEA TVIG
//