GenomeNet

Database: UniProt
Entry: D1BM89_VEIPT
LinkDB: D1BM89_VEIPT
Original site: D1BM89_VEIPT 
ID   D1BM89_VEIPT            Unreviewed;       204 AA.
AC   D1BM89;
DT   19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2010, sequence version 1.
DT   08-MAY-2019, entry version 61.
DE   RecName: Full=Probable nicotinate-nucleotide adenylyltransferase {ECO:0000256|HAMAP-Rule:MF_00244};
DE            EC=2.7.7.18 {ECO:0000256|HAMAP-Rule:MF_00244};
DE   AltName: Full=Deamido-NAD(+) diphosphorylase {ECO:0000256|HAMAP-Rule:MF_00244};
DE   AltName: Full=Deamido-NAD(+) pyrophosphorylase {ECO:0000256|HAMAP-Rule:MF_00244};
DE   AltName: Full=Nicotinate mononucleotide adenylyltransferase {ECO:0000256|HAMAP-Rule:MF_00244};
DE            Short=NaMN adenylyltransferase {ECO:0000256|HAMAP-Rule:MF_00244};
GN   Name=nadD {ECO:0000256|HAMAP-Rule:MF_00244};
GN   OrderedLocusNames=Vpar_0815 {ECO:0000313|EMBL:ACZ24496.1};
OS   Veillonella parvula (strain ATCC 10790 / DSM 2008 / JCM 12972 / Te3)
OS   (Veillonella alcalescens).
OC   Bacteria; Firmicutes; Negativicutes; Veillonellales; Veillonellaceae;
OC   Veillonella.
OX   NCBI_TaxID=479436 {ECO:0000313|EMBL:ACZ24496.1, ECO:0000313|Proteomes:UP000007968};
RN   [1] {ECO:0000313|Proteomes:UP000007968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10790 / DSM 2008 / JCM 12972 / Te3
RC   {ECO:0000313|Proteomes:UP000007968};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Ivanova N., Mikhailova N., Saunders E., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.F.,
RA   Hugenholtz P., Woyke T., Wu D., Wellnitz S., Schneider S., Gronow S.,
RA   Klenk H.P., Eisen J.A.;
RT   "The complete genome of Veillonella parvula DSM 2008.";
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ACZ24496.1, ECO:0000313|Proteomes:UP000007968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10790 / DSM 2008 / JCM 12972 / Te3
RC   {ECO:0000313|Proteomes:UP000007968};
RX   PubMed=21304678; DOI=10.4056/sigs.521107;
RA   Gronow S., Welnitz S., Lapidus A., Nolan M., Ivanova N.,
RA   Glavina Del Rio T., Copeland A., Chen F., Tice H., Pitluck S.,
RA   Cheng J.F., Saunders E., Brettin T., Han C., Detter J.C., Bruce D.,
RA   Goodwin L., Land M., Hauser L., Chang Y.J., Jeffries C.D., Pati A.,
RA   Mavromatis K., Mikhailova N., Chen A., Palaniappan K., Chain P.,
RA   Rohde M., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P., Lucas S.;
RT   "Complete genome sequence of Veillonella parvula type strain (Te3).";
RL   Stand. Genomic Sci. 2:57-65(2010).
CC   -!- FUNCTION: Catalyzes the reversible adenylation of nicotinate
CC       mononucleotide (NaMN) to nicotinic acid adenine dinucleotide
CC       (NaAD). {ECO:0000256|HAMAP-Rule:MF_00244}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-
CC         NAD(+) + diphosphate; Xref=Rhea:RHEA:22860, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57502,
CC         ChEBI:CHEBI:58437; EC=2.7.7.18; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00244, ECO:0000256|SAAS:SAAS01124450};
CC   -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; deamido-
CC       NAD(+) from nicotinate D-ribonucleotide: step 1/1.
CC       {ECO:0000256|HAMAP-Rule:MF_00244, ECO:0000256|SAAS:SAAS00999967}.
CC   -!- SIMILARITY: Belongs to the NadD family. {ECO:0000256|HAMAP-
CC       Rule:MF_00244, ECO:0000256|SAAS:SAAS01025576}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001820; ACZ24496.1; -; Genomic_DNA.
DR   RefSeq; WP_012864285.1; NC_013520.1.
DR   STRING; 479436.Vpar_0815; -.
DR   EnsemblBacteria; ACZ24496; ACZ24496; Vpar_0815.
DR   GeneID; 8636276; -.
DR   KEGG; vpr:Vpar_0815; -.
DR   PATRIC; fig|479436.6.peg.794; -.
DR   eggNOG; ENOG4108Z1W; Bacteria.
DR   eggNOG; COG1057; LUCA.
DR   HOGENOM; HOG000262780; -.
DR   KO; K00969; -.
DR   OMA; DPIHLGH; -.
DR   OrthoDB; 1433958at2; -.
DR   BioCyc; VPAR479436:G1GGP-829-MONOMER; -.
DR   UniPathway; UPA00253; UER00332.
DR   Proteomes; UP000007968; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004515; F:nicotinate-nucleotide adenylyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd02165; NMNAT; 1.
DR   Gene3D; 3.40.50.620; -; 1.
DR   HAMAP; MF_00244; NaMN_adenylyltr; 1.
DR   InterPro; IPR004821; Cyt_trans-like.
DR   InterPro; IPR005248; NadD/NMNAT.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   Pfam; PF01467; CTP_transf_like; 1.
DR   TIGRFAMs; TIGR00125; cyt_tran_rel; 1.
DR   TIGRFAMs; TIGR00482; TIGR00482; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00244,
KW   ECO:0000256|SAAS:SAAS00459924};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007968};
KW   NAD {ECO:0000256|HAMAP-Rule:MF_00244, ECO:0000256|SAAS:SAAS00459916};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00244,
KW   ECO:0000256|SAAS:SAAS00459927};
KW   Nucleotidyltransferase {ECO:0000256|HAMAP-Rule:MF_00244,
KW   ECO:0000256|SAAS:SAAS00459933, ECO:0000313|EMBL:ACZ24496.1};
KW   Pyridine nucleotide biosynthesis {ECO:0000256|HAMAP-Rule:MF_00244,
KW   ECO:0000256|SAAS:SAAS00086506};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00244,
KW   ECO:0000256|SAAS:SAAS00459928, ECO:0000313|EMBL:ACZ24496.1}.
FT   DOMAIN        9    176       CTP_transf_like. {ECO:0000259|Pfam:
FT                                PF01467}.
SQ   SEQUENCE   204 AA;  23293 MW;  1DC7B70E1F5DE2DD CRC64;
     MVDKRRIGII GGTFNPIHLG HLMIAEVACE SFNLEKVIFV PAHIPPHKQY DVIDSHHRYA
     MTAAAVSDNP NFEISDVEMR REGPSYTVDT IQYFKKLYGP TVEFYFIAGT DTIRALPTWK
     FIDELIDEVH FIGATRPDGS SAIDSTLDEL GSKAREKIHV MEVPEMKLSA TYLRERLRSG
     KTVRYMLPKC VVDYIEENHI YGKE
//
DBGET integrated database retrieval system