ID D1NZC4_9GAMM Unreviewed; 445 AA.
AC D1NZC4;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE SubName: Full=Dual specificity phosphatase, catalytic domain protein {ECO:0000313|EMBL:EFB73821.1};
GN ORFNames=PROVRUST_05094 {ECO:0000313|EMBL:EFB73821.1};
OS Providencia rustigianii DSM 4541.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Providencia.
OX NCBI_TaxID=500637 {ECO:0000313|EMBL:EFB73821.1, ECO:0000313|Proteomes:UP000005512};
RN [1] {ECO:0000313|EMBL:EFB73821.1, ECO:0000313|Proteomes:UP000005512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4541 {ECO:0000313|EMBL:EFB73821.1,
RC ECO:0000313|Proteomes:UP000005512};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFB73821.1}.
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DR EMBL; ABXV02000011; EFB73821.1; -; Genomic_DNA.
DR RefSeq; WP_006813173.1; NZ_GG703817.1.
DR AlphaFoldDB; D1NZC4; -.
DR STRING; 500637.PROVRUST_05094; -.
DR GeneID; 76391673; -.
DR eggNOG; COG0671; Bacteria.
DR eggNOG; COG2453; Bacteria.
DR HOGENOM; CLU_031173_0_0_6; -.
DR Proteomes; UP000005512; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd14527; DSP_bac; 1.
DR CDD; cd03386; PAP2_Aur1_like; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR026841; Aur1/Ipt1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR47216; -; 1.
DR PANTHER; PTHR47216:SF4; OS01G0859400 PROTEIN; 1.
DR Pfam; PF00782; DSPc; 1.
DR Pfam; PF14378; PAP2_3; 1.
DR SMART; SM00195; DSPc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 362..423
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 445 AA; 51418 MW; F158E00356BAAA4D CRC64;
MTAVSSNIAT TSRRQIWIYG LLWLVFLAPF FFLTYGQVNH YTATLPNVPS YVFSWEQHIP
FIPWTIIPYW SIDLFYGISL FICVTRQEQG IHGLRLVMAS VIACVGFLLF PLKFSFPRPD
THSAFGWMFD SLELFDLPYN QAPSLHIILL WLLWLRFRAH TPNQWRWLLN AWSILILISV
LTTWQHHFID VVTGFAAGVM ISYLLPINTR WQWHYTGSPR SLKIAKNYGL GALFCFVISF
SVQGFAWWLL WPAVALTLVT LGYLGAGASV FQKTPSGHVS LSAAWVLLPY RLIAWGTYHY
YSKHCRQPST INEKVVLGGR PLYPLQTQAV LDMTCEWPRN VYSQRQEYAS QPQIDLLPLS
PEDIERAVHT MDRLAQHGAV YVHCKLGYSR SATVVVAWLV HQKMAKTLNE AIRQVEQARP
HVILNCATIE QLNNWYQQFH IQREQ
//
