ID D1PNQ3_9FIRM Unreviewed; 331 AA.
AC D1PNQ3;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=N-acetylneuraminate synthase {ECO:0000313|EMBL:EFB76188.1};
DE EC=2.5.1.56 {ECO:0000313|EMBL:EFB76188.1};
GN Name=neuB {ECO:0000313|EMBL:EFB76188.1};
GN ORFNames=SUBVAR_05974 {ECO:0000313|EMBL:EFB76188.1};
OS Subdoligranulum variabile DSM 15176.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Subdoligranulum.
OX NCBI_TaxID=411471 {ECO:0000313|EMBL:EFB76188.1, ECO:0000313|Proteomes:UP000003438};
RN [1] {ECO:0000313|EMBL:EFB76188.1, ECO:0000313|Proteomes:UP000003438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15176 {ECO:0000313|EMBL:EFB76188.1,
RC ECO:0000313|Proteomes:UP000003438};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFB76188.1}.
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DR EMBL; ACBY02000023; EFB76188.1; -; Genomic_DNA.
DR RefSeq; WP_007047348.1; NZ_GG704769.1.
DR AlphaFoldDB; D1PNQ3; -.
DR STRING; 411471.SUBVAR_05974; -.
DR GeneID; 78306139; -.
DR eggNOG; COG2089; Bacteria.
DR HOGENOM; CLU_040465_0_0_9; -.
DR OrthoDB; 9814210at2; -.
DR Proteomes; UP000003438; Unassembled WGS sequence.
DR GO; GO:0050462; F:N-acetylneuraminate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR CDD; cd11615; SAF_NeuB_like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR InterPro; IPR006190; AFP_Neu5c_C.
DR InterPro; IPR036732; AFP_Neu5c_C_sf.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR020007; N-AcNeuraminate_synthase.
DR InterPro; IPR013132; Neu5Ac_N.
DR InterPro; IPR013974; SAF.
DR NCBIfam; TIGR03569; NeuB_NnaB; 1.
DR PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR Pfam; PF03102; NeuB; 1.
DR Pfam; PF08666; SAF; 1.
DR SMART; SM00858; SAF; 1.
DR SUPFAM; SSF51269; AFP III-like domain; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50844; AFP_LIKE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000003438};
KW Transferase {ECO:0000313|EMBL:EFB76188.1}.
FT DOMAIN 279..331
FT /note="AFP-like"
FT /evidence="ECO:0000259|PROSITE:PS50844"
SQ SEQUENCE 331 AA; 35982 MW; 556CA9C6ED05FEE3 CRC64;
MPVTIIAEAG VNHNGDLEMA KRMALAAKEC GADIVKYQTA VPELVVSKFA EKAAYQKETT
DAAESQLDMI RKLHFSFDGH RELKEYCDSI GIQYLSAPFD IPSVRFLGTL NLPLIKIPSG
EITNLPYLEE VAKLHTPVLL STGMSNLNEI TDALGILDDG GCPEATVLHC NTQYPTPYED
ANLTAMLELF DQFGLPVGLS DHTPGWECDV AAAVLGATVI EKHFTLDKTL PGPDQQASLD
PTEFKAMVQA VRHVEAALGD GHKHLTASEA PNKAVARKSI VAARPIKAGE VFTADNLTTK
RPGDGISPMR WYDVLGKTAP RDFDEDEKIQ L
//
