ID D1PTE5_9BACT Unreviewed; 474 AA.
AC D1PTE5;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Peptidase, M16 family {ECO:0000313|EMBL:EFA45369.1};
DE EC=3.4.24.- {ECO:0000313|EMBL:EFA45369.1};
GN ORFNames=HMPREF0645_0230 {ECO:0000313|EMBL:EFA45369.1};
OS Hallella bergensis DSM 17361.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hallella.
OX NCBI_TaxID=585502 {ECO:0000313|EMBL:EFA45369.1, ECO:0000313|Proteomes:UP000003160};
RN [1] {ECO:0000313|EMBL:EFA45369.1, ECO:0000313|Proteomes:UP000003160}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17361 {ECO:0000313|EMBL:EFA45369.1,
RC ECO:0000313|Proteomes:UP000003160};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFA45369.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACKS01000014; EFA45369.1; -; Genomic_DNA.
DR AlphaFoldDB; D1PTE5; -.
DR eggNOG; COG0612; Bacteria.
DR HOGENOM; CLU_009902_3_2_10; -.
DR Proteomes; UP000003160; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR11851:SF149; GH01077P; 1.
DR PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:EFA45369.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003160}.
FT DOMAIN 70..208
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 215..409
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 474 AA; 53611 MW; 54EB852CFE4023A8 CRC64;
MLWFFKKLRE FTECRGFLPI LSMQTTVPSL QISEKKGTIQ NEIVYFCSEM KYNTVTLDNG
LRIIHLPSSS PVVYCGYQIR AGSRDEQPGE EGLAHFCEHA TFKGTEHRRA WNVLNCLESV
GGDLNAFTTK EDTTYHAAVL KEHIGRAIDI LTDIVFHSTY PQAELDKEAE VVCDEIQSCN
DSPSELIYDE FENLIFKGHP LGHAILGTTE NVRTFDAETV RRFTRTYYRP DNAIFFVYGD
VPFSKVVKNL CRIHNTAPAC TDPSQAADAQ THADNMGVAS SGIFKPFSSE AHGETIIMNR
QTHQTHVMLG SRAYDIHNSK RMGLYLLNNM LGGPGMNARL NLTLRERHGL VYTVESTMVS
YGDAGLWCTY FGCDPHDLKR CLRLVRKELD SLIRLPITPT RLHAAKKQLK GQIGVACDNR
ENFALDFGKS FLHYGWEKDI NALYKDIDGI TAQDIHEVAT EIFAPERMTT LIYQ
//
