ID D1PUQ8_9BACT Unreviewed; 1115 AA.
AC D1PUQ8;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=HMPREF0645_0693 {ECO:0000313|EMBL:EFA44897.1};
OS Hallella bergensis DSM 17361.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hallella.
OX NCBI_TaxID=585502 {ECO:0000313|EMBL:EFA44897.1, ECO:0000313|Proteomes:UP000003160};
RN [1] {ECO:0000313|EMBL:EFA44897.1, ECO:0000313|Proteomes:UP000003160}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17361 {ECO:0000313|EMBL:EFA44897.1,
RC ECO:0000313|Proteomes:UP000003160};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFA44897.1}.
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DR EMBL; ACKS01000031; EFA44897.1; -; Genomic_DNA.
DR AlphaFoldDB; D1PUQ8; -.
DR eggNOG; COG1074; Bacteria.
DR HOGENOM; CLU_010638_0_0_10; -.
DR OrthoDB; 9810135at2; -.
DR Proteomes; UP000003160; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 1.10.3170.10; Recbcd, chain B, domain 2; 1.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF64; ATP-DEPENDENT DNA HELICASE REP; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000003160}.
FT DOMAIN 1..469
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 508..762
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 13..20
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1115 AA; 128358 MW; 67BB7D1CAE368140 CRC64;
MTPNNKPLTV YKASAGSGKT FTLAVEYIKL LVQEPQNYRY ILAVTFTNKA TEEMKRRILG
QLYGIANALP DSESYMDALH KAFPAMADRA IRERVKEALG LILHHYHEFR VETIDSFFQR
ILHNLSRELG LTANLQVGLN DFEVESQAVD NIIDNIQQDN DPLLAWLMDF IKEKVNDEKN
WNVIGPIKEF GKNIFKEFYK DHQKELRRIM NDPGFFKAYN AKLRSMKTEA YQVMADFAKA
YQDLAGKHGL EDAHFNRGSQ NAPGYFAKLA SGDFLDDKFP SKTMLKAIED HTSMVKKSDL
NTPEGQIIVS EVGVLLDRAE KERKKQCAVI NSVDLTLRNL YELRLLGRIE QEVSTINTAN
NNYLLSNTQK LLNDLIDKQD SPFIYEKTGA QLRYIMIDEF QDTSTVQWNN FKVLLDDCMA
HNNGSLIVGD VKQSIYRWRN GDWRLLQNLT PENDNRILIK PLDTNYRSKQ NIIRFNNAFF
KIAAQTTSDD ALAALQALDA PPQLLREALD IRQAYDDVVQ KVSPKHQTED ASRAGSVTIK
LLPRDNYEAQ VIEEVSRILE HLLEAGIPPK KIAILVRKNN HIQLLANYFQ QNPITVNGEA
QMVRMVSDEA FRLDASLAVC TLVRAMHLLT HPDDKLAAAA LVKAYHKIGH DGEETDDSQL
FVGNDNLLTL LPEEMTEHWD ELLSTPLIDM AEQLYRIFRL DRLDGQSAYV CAFFDHLSLF
MRNHVASVEE FIEEWENSIS GKAIHSDEVN GIRLLTVHKS KGLEFDNVII PYCDWDLEMQ
GEVLWMMPPS EPFSQLPVVP VNLYAKRLQR SIYNIDYQSE HLKNYVDNLN MLYVAFTRAG
SNLFVIGRNQ APQFPSLLIR QVIDHCQAES DGKAEDKTQD PEVEPALMMP KHTVEDDEDD
ITTFRIGRLC VDEETHKEQT RNVFEQTEEG IRTAIRNYEA KACFRQSNDS ADFVTPDEEM
ERLEKRQSYI QTGNILHTLL ASIRNVDDID RAIDQLEFDG VLYDKPMNRE ELRRMITERM
QTQQVADWFA PTGQVFNECT ILSYDSHLDR VRENRPDRVI WNGKEMVVID FKTGREHEEH
HVQVRNYMDL LRGMGYASVS GYLWYIRTNR VVSVK
//
