ID D1PYX5_9BACT Unreviewed; 655 AA.
AC D1PYX5;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Alpha-galactosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF0645_2160 {ECO:0000313|EMBL:EFA43391.1};
OS Hallella bergensis DSM 17361.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hallella.
OX NCBI_TaxID=585502 {ECO:0000313|EMBL:EFA43391.1, ECO:0000313|Proteomes:UP000003160};
RN [1] {ECO:0000313|EMBL:EFA43391.1, ECO:0000313|Proteomes:UP000003160}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17361 {ECO:0000313|EMBL:EFA43391.1,
RC ECO:0000313|Proteomes:UP000003160};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFA43391.1}.
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DR EMBL; ACKS01000081; EFA43391.1; -; Genomic_DNA.
DR RefSeq; WP_007174263.1; NZ_GG704781.1.
DR AlphaFoldDB; D1PYX5; -.
DR eggNOG; COG1876; Bacteria.
DR HOGENOM; CLU_011166_1_1_10; -.
DR OrthoDB; 1109141at2; -.
DR Proteomes; UP000003160; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:UniProt.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR029483; GH97_C.
DR InterPro; IPR019563; GH97_catalytic.
DR InterPro; IPR029486; GH97_N.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR35803; GLUCAN 1,4-ALPHA-GLUCOSIDASE SUSB-RELATED; 1.
DR PANTHER; PTHR35803:SF2; RETAINING ALPHA-GALACTOSIDASE; 1.
DR Pfam; PF14509; GH97_C; 1.
DR Pfam; PF14508; GH97_N; 1.
DR Pfam; PF10566; Glyco_hydro_97; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000003160};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..655
FT /note="Alpha-galactosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003026076"
FT DOMAIN 25..289
FT /note="Glycosyl-hydrolase 97 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14508"
FT DOMAIN 299..557
FT /note="Glycosyl-hydrolase 97 catalytic"
FT /evidence="ECO:0000259|Pfam:PF10566"
FT DOMAIN 559..652
FT /note="Glycosyl-hydrolase 97 C-terminal oligomerisation"
FT /evidence="ECO:0000259|Pfam:PF14509"
SQ SEQUENCE 655 AA; 73999 MW; 81119DC7D93E0B04 CRC64;
MKKTFILSLS MMVALSSWAT EKNFASPNGK LVVTVSDDGG RATYQLTYDG KQMLGTSSLG
LKTNIGDFTQ GLTMTVKTDE EFTNKYSMTR TKTSRVEQQA RRVTLSFTNK KERTIEVDFY
IANNDVAYRY RLLRPKQNNP KCAVIYGEVS SFNLPTHTTT FLSPQIQPMT GWERTKPSYE
EVFSSDAPMD KKSQYGVGYT FPALFHVGTD GWVLVSETGV SGEYVGARLS DYQAGKGYTI
AYPQEGEMNG NGTPWAAISL PGETPWRTIT VGATLAPIVE TTIPYDVVEE QYASSENYKP
GRYTWSWLIW QDGSINYDDQ VKFVDLAAKM GYEYNLVDNW WDTQIGRERI EQLSKYAQSK
GVSLMLWYNS NGFENDAPQG PRNIMHRAIN RKKEMAWLQK IGVKGIKVDF FAGDKQQTMQ
LYEDILSDAN DFGLQVIFHG CTLPRGWERM YPNFVASEAA LASENVFFTS EHAQREGYDM
ALHPFGRNAV ASFDWGGVMM NRMMSKDNKS RHRRYTSDVF EMATGITNQC SVNCVEVTPN
VVDELPQHQI DFLRQLPTTW DETKFIDGYP TKYAVVARKS GGKWYVGGIN GTNEAKHLNL
NLPMLAGKTV QYYLDKKAKK GQMWPDSELR TLKVDRNGKV KVTIQPMGGI VLVGE
//
