ID D1VV94_9FIRM Unreviewed; 2312 AA.
AC D1VV94;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Repeat protein {ECO:0000313|EMBL:EFA89511.1};
GN ORFNames=HMPREF0628_1347 {ECO:0000313|EMBL:EFA89511.1};
OS Peptoniphilus lacrimalis 315-B.
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC Peptoniphilus.
OX NCBI_TaxID=596330 {ECO:0000313|EMBL:EFA89511.1, ECO:0000313|Proteomes:UP000005711};
RN [1] {ECO:0000313|EMBL:EFA89511.1, ECO:0000313|Proteomes:UP000005711}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=315-B {ECO:0000313|EMBL:EFA89511.1,
RC ECO:0000313|Proteomes:UP000005711};
RA Durkin A.S., Madupu R., Torralba M., Methe B., Sutton G., Strausberg R.L.,
RA Nelson K.E.;
RT "Genome Sequence of Peptoniphilus lacrimalis 315-B.";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240, ECO:0000256|RuleBase:RU003355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFA89511.1}.
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DR EMBL; ADDO01000063; EFA89511.1; -; Genomic_DNA.
DR RefSeq; WP_004826036.1; NZ_ADDO01000063.1.
DR eggNOG; COG1404; Bacteria.
DR eggNOG; COG1579; Bacteria.
DR eggNOG; COG4412; Bacteria.
DR eggNOG; COG4625; Bacteria.
DR eggNOG; COG5263; Bacteria.
DR Proteomes; UP000005711; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.60.40.4270; Listeria-Bacteroides repeat domain; 2.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR013378; InlB-like_B-rpt.
DR InterPro; IPR042229; Listeria/Bacterioides_rpt_sf.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR001119; SLH_dom.
DR NCBIfam; TIGR02543; List_Bact_rpt; 1.
DR PANTHER; PTHR43399:SF5; CELL WALL-ASSOCIATED PROTEASE; 1.
DR PANTHER; PTHR43399; SUBTILISIN-RELATED; 1.
DR Pfam; PF09479; Flg_new; 3.
DR Pfam; PF20773; InhA-like_MAM; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF00395; SLH; 3.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51272; SLH; 3.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000005711};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 2131..2191
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT DOMAIN 2192..2255
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT DOMAIN 2258..2312
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT REGION 2068..2091
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 63..92
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2073..2089
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 208
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 254
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 425
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 2312 AA; 261365 MW; 603AF065FCACBF24 CRC64;
MKKLNKILAI ILFTAILFTD FIPVLAISKS SEDISKKLSE NLIRSKNDEF FDVIVKLKKE
VNSQRIKNDV KNANAEKSKE ELQKEIRKEI VNESKELAKS TQASILEILK NEKNKGNVKS
YESFFIINCV NLVARKSVIV ELAKRDDVEK IIENKVIKVE KPEKNEIIRM SRSAYDIHIP
WNLEAINAYK AQRYTKDCNN EVVVGIIDSG VDSTHSAISK NYRGNDSSLA AYSWYNTITG
KDGSQEKPYD DRGHGTHVCG TILGSKENAL LGVAPKAKWI GVKVFDQDGE TNNVKLLKAG
EWIMAPNGDP TKAPKVVNNS WGGNSNDGFF QEIVKKWREA GIFPVFSAGN VGPFNDGGDD
SIGTPGAYPE SYAVGAIRKD EHIAKFSLRG KSTYTNKIKP DIVAPGVNIL SCIPGEKYTI
YTGTSMAAPH VTGVIALMLQ VNPNLTVDQI ENILNETALP LKDEYYTTTP NNGYGYGKVN
AVSAVQLAKG QEKGKDIKKD NIAILSGRLL AHGQDTQAPV ISHNPINKIF TTYKTTFDVD
AKDNTGVKSV KLLLDLGNGY KSYDLELKRG NKVDGYYSTN IPVETFKGVS EGKYYIEVID
INDKVTKTPV YPFEVQKGIG IGYVNNFESD ISGFDFGGEA KLFKWGKIKS DEANNKVIGI
EPYDKIRGNS IVVMPPIDLT GENRKAALTF KHWYDLGNSE YAFFDTAEVW IAEAKEDSTP
DTLQWKLKRT YKNSSKGWTN EYIDLSEYFG KKICIMFGFR PNGEWKSEGK GWYIDDLKVE
EVSKEVPEKP SKSLNLRNKK DGRIIYSFLP IKNDKVTAYE LYRSKSENSG FECIKTVLKG
DKNNGFGKYS IDLSDTPKPQ KGTYYYYAVA KIGDNKSEPS ETKSVTFTEG KEFKSFDFEN
GEEGWTSSIN GDEKSLWEFG NLKYGDQYST EYKKPIERQS LGKNDGMKMW ATNMNDYRSP
NTKYALVSPS MDLSSLSDGT LYYQNWFGSS GKRYSDDYDT YNQDIGEIYL SKDAGKTWKK
FYTLDEKNLE KDGIIHAWFT NKVEIPKDYL VKDFKVKFLL ETGSDTGSSD SAQSGGWYID
DVTINSKNLE DKNIVIDKNP APFKLTNLER PASENKSVLP LSGKIIIAEQ NSLAKVIATV
QTEPGTGAFS IKLPVGDYLI VGSADGYKNS KHDYITLKKD GLNKDIYLEK AGGASVTVNL
KDYNYDEFKG LGKVTLYKKG EIAPIAEKKG VNVTFENLYP GDYIYIVNSD GFKKIEQEFA
LDGHSRPFNA RLHEKLFPQK ESSVGYTDET PLELAGMDLK NRAFANKITN DKIAQIKEIS
YFITKTKDVD LKGSKYRISI YDKNDDDELP GKILFSKDLT FEKEGWNKID VSNVQVWGDY
YIAFTKLDGN LALGIDNKKE NTMSYQMFND AWDVPDTKGT YMLGAKVEEC SDKENKEKCT
ISFDSNGGSG KMESIEVDKK SNYIVPECIF TAPEGKEFRA WQVYTKEIQA GESQYVFENV
TFKALWKDKK TENKEKLEPV MPFPMMGQTN VTNFDHFITY KNETESDEYL KSIEKVIVKH
KGKTQEITGA KGIDSTDPLG NANKKLAFPF ESKLDIDDTI TIISSKYKNV LIKISLVTEF
GNDIYYNISA NVEGQKIVRT IHFDANGGTN NMKDVEVENG SIYSLPECTI TPPKGYEFKA
WEYLDVESEV GHKYQINKDV TIKAIWKKIP TKNITIHYDS NAGEGEMPDE SKLENEKFII
PESRFTPPQG KEFDAWEIND QRKYPGEELV LSENITLKAI WTQKLEKTKD PIEPILTEVK
SDDPSNKKAN CKHFIGYKKE DREYIDAINL ITIKHNGEII KKYHITKEDG KYEVLDGIGK
TKKDMTSIVF NSNFFFSRDD EIIICARGYK DLRLHIAAAD DMVMNALYTT EIISKVKFET
FDGSKVDDQV IKVTPTWAEN VKKPKTDPTK EGYIFKGWYK DSACKENFDF NSKIISDTSI
YAKWEKEIKK FTISFIGNGG TGEMNTIEKD KDQKYILPIS TFIPAEGKEF DAWEINGQRK
SPGEEITINS DTQIKAIWKD KILPPGPKVE PEIELKPSPE IKHENNDSGN NNKNHYFPWS
NESKVQKDTS KVNSIVNSSE ENNKFMENTK TAYTIPKDAQ KHWAKEAIEY CLSKGYFKDI
VKDQKFEPEK QITRGEFITI LARFAGAKES NTKISFTDID KNMYYAPFVA WAKENNITAG
TGIGKFSPDK PISRAEMTTM LYRFLKSIKI NVKSLDKNID FKDKDKIPSW AKEAIKEMVD
FGILNGNDDG TFNPNGKFKR CQMSQIIYNL SK
//
