GenomeNet

Database: UniProt
Entry: D1VZM5_9BACT
LinkDB: D1VZM5_9BACT
Original site: D1VZM5_9BACT 
ID   D1VZM5_9BACT            Unreviewed;       470 AA.
AC   D1VZM5;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   13-FEB-2019, entry version 58.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:EFA97357.1};
GN   ORFNames=HMPREF9019_2051 {ECO:0000313|EMBL:EFA97357.1};
OS   Prevotella timonensis CRIS 5C-B1.
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=679189 {ECO:0000313|EMBL:EFA97357.1, ECO:0000313|Proteomes:UP000004001};
RN   [1] {ECO:0000313|EMBL:EFA97357.1, ECO:0000313|Proteomes:UP000004001}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CRIS 5C-B1 {ECO:0000313|EMBL:EFA97357.1,
RC   ECO:0000313|Proteomes:UP000004001};
RA   Durkin A.S., Madupu R., Torralba M., Methe B., Sutton G.,
RA   Strausberg R.L., Nelson K.E.;
RT   "Genome Sequence of Prevotella timonensis CRIS 5C-B1.";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EFA97357.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; ADEF01000039; EFA97357.1; -; Genomic_DNA.
DR   RefSeq; WP_008124183.1; NZ_ADEF01000039.1.
DR   STRING; 679189.HMPREF9019_2051; -.
DR   EnsemblBacteria; EFA97357; EFA97357; HMPREF9019_2051.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   BioCyc; GCF_000177055-HMP:HMPREF9019_RS06455-MONOMER; -.
DR   Proteomes; UP000004001; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000004001};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004001}.
FT   DOMAIN      165    297       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      376    445       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     173    180       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   470 AA;  53978 MW;  7167DAD4FCBEE89B CRC64;
     MNVSPNEAWD KTLTLIRENV SEQQYNTWFK PIVYESFEES TRTLLVQVPS PFVYEYLEEN
     YIDLLSKVLR RTFCDQIRLK YRIVTDQEHH LTQDVEAEQT DLSVKTQLAK TRVNESPTTL
     DAAQPQQLDP NLNPHQTFNN YIEGDSNKLP RSVGLSIAEH PRKTQFNPMF VYGPSGCGKT
     HLINAIGMRT KQLYAQKRVL YVSARLFQVQ YTNAVLQNSI NDFINFYQTI DLLIVDDIQE
     WMTATKTQDT FFHIFNHLFR NGKRIILASD RPPVDLKGMN ERLLTRFSCG LIAELEKPNV
     QLCIDILNSK IRKDGLQILE DVVQFIAETA NGSVRDLEGV INSLLAYSVV YNSTVDMRLA
     QRVIQRAVKI DDKPLTIDEI LEKVCNHFNV SVSAVNGRSR KQDLVTARQV SMYLAQKYTK
     MPASRIGKLV GGRDHSTVIH SCSRVEQRLQ VDSMFSNELM SIENSFKLKN
//
DBGET integrated database retrieval system