ID D1W2B5_9BACT Unreviewed; 638 AA.
AC D1W2B5;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=ATP-dependent DNA helicase, RecQ family {ECO:0000313|EMBL:EFA96588.1};
DE EC=3.6.1.- {ECO:0000313|EMBL:EFA96588.1};
GN ORFNames=HMPREF9019_0311 {ECO:0000313|EMBL:EFA96588.1};
OS Hoylesella timonensis CRIS 5C-B1.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hoylesella.
OX NCBI_TaxID=679189 {ECO:0000313|EMBL:EFA96588.1, ECO:0000313|Proteomes:UP000004001};
RN [1] {ECO:0000313|EMBL:EFA96588.1, ECO:0000313|Proteomes:UP000004001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRIS 5C-B1 {ECO:0000313|EMBL:EFA96588.1,
RC ECO:0000313|Proteomes:UP000004001};
RA Durkin A.S., Madupu R., Torralba M., Methe B., Sutton G., Strausberg R.L.,
RA Nelson K.E.;
RT "Genome Sequence of Prevotella timonensis CRIS 5C-B1.";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFA96588.1}.
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DR EMBL; ADEF01000072; EFA96588.1; -; Genomic_DNA.
DR RefSeq; WP_008126114.1; NZ_ADEF01000072.1.
DR AlphaFoldDB; D1W2B5; -.
DR eggNOG; COG0514; Bacteria.
DR Proteomes; UP000004001; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EFA96588.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EFA96588.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000004001}.
FT DOMAIN 28..196
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 217..366
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 638 AA; 73179 MW; 748C669B1573A87A CRC64;
MPVHDKYLSI LQQYWGYKDF RGIQREIIES IGQQRDTLGL MPTGGGKSIT FQVPALAQPG
ICLVITPLIA LMKDQVQHLK EKGITAAAIF SGMTRREILK TLDNCIFGDI KLLYISPERI
GSELFLMKLR RMNVSFITVD EAHCISQWGY DFRPAYLNIA DIRKEKPAAP LLALTATATP
EVVEDIQQQL GFKEKNVFQM SFERSNLTYV VRTAQDKYQE ILHILQSLPG CAIIYVRSRK
RTKEVATLLN ACDIPATYYH AGLEHSVKDE RQRAWQTDQI RVMVATNAFG MGIDKPDVRV
VIHIDCPDSL EAYFQEAGRA GRDGQRSYAV LLHNTSDKHK LNKRIEDNFP EKDYIKDVYQ
HLAYYFEIGL GSGSGHTFTF DIGKFCAVFH YFPIPVNSAL LILSRAGYLE YDTDPDSNAR
VMFLLDRNEL YKLNQVSPLQ EKVITSLLRT YGGLFTDYVY IDEALLAQQA GITREQLYLI
LKGLTQRRIL HFIPQRKMPF ITYAKDREAI ENMVIPKAVY EERKEQFSKR IKSVIRYAEN
NEVCRSKQLL RYFGDVQAKD CLRCDVCLDQ GLQRNSTITT NEIKQTILHG LEDKERHHIT
ELDKLAFPEK LLDQVLEQLV AEEIIVLEGS YIYLANKG
//
