ID D1W2R6_9BACT Unreviewed; 376 AA.
AC D1W2R6;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Addiction module antidote protein HigA {ECO:0000313|EMBL:EFA93142.1};
GN Name=higA {ECO:0000313|EMBL:EFA93142.1};
GN ORFNames=HMPREF0650_0685 {ECO:0000313|EMBL:EFA93142.1};
OS Hoylesella buccalis ATCC 35310.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hoylesella.
OX NCBI_TaxID=679190 {ECO:0000313|EMBL:EFA93142.1, ECO:0000313|Proteomes:UP000005283};
RN [1] {ECO:0000313|EMBL:EFA93142.1, ECO:0000313|Proteomes:UP000005283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35310 {ECO:0000313|EMBL:EFA93142.1,
RC ECO:0000313|Proteomes:UP000005283};
RA Durkin A.S., Madupu R., Torralba M., Methe B., Sutton G., Strausberg R.L.,
RA Nelson K.E.;
RT "Genome Sequence of Prevotella buccalis ATCC 35310.";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain fatty acyl-CoA assimilation
CC regulator (ScfR) family. {ECO:0000256|ARBA:ARBA00007227}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFA93142.1}.
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DR EMBL; ADEG01000011; EFA93142.1; -; Genomic_DNA.
DR AlphaFoldDB; D1W2R6; -.
DR eggNOG; COG2856; Bacteria.
DR eggNOG; COG3093; Bacteria.
DR Proteomes; UP000005283; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010359; IrrE_HExxH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR013430; Toxin_antidote_HigA.
DR NCBIfam; TIGR02607; antidote_HigA; 1.
DR PANTHER; PTHR36924; ANTITOXIN HIGA-1; 1.
DR PANTHER; PTHR36924:SF1; ANTITOXIN HIGA-1; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF06114; Peptidase_M78; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT DOMAIN 27..81
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 376 AA; 43179 MW; 22CAD2FCAA5C505E CRC64;
MKLIVHIMAT RSNRLVPVRA IHPGEILREE LRERGIKQKD FAKQIGMQAT HLSEFIRGKR
NLNDDLAMKL ENHLGIPYKT WMSLHNGYMY DSKAVSKKQS EEQIARSFED ACARVFNLKL
LYKKLNLAVL PLLERVKEIK SLFSFDLLSS AEMSKQVAGL YKHSDKVQID EKNMQTWLLL
SWLATSREKV ERTYVHGNGI KAADTIAKLA NERKLTAKAI KDCLYQNGIG YVVVEKLDKT
PVDAFSTYVN QHPIVTVTYR YNDIDKLAFD VLHELCHIEK HFSEEHTSFI SIEGTIYSKD
PREKEANDFA KEHLIPCEVW NKILSGKSSS LSPHIVVKAI AKEAEKYGIS PTIAVSRYKH
DTNWYQTSAY KSSKIY
//
