ID   D1YYU3_METPS            Unreviewed;       628 AA.
AC   D1YYU3;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   OrderedLocusNames=MCP_1543 {ECO:0000313|EMBL:BAI61615.1};
OS   Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 /
OS   SANAE).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=304371 {ECO:0000313|EMBL:BAI61615.1, ECO:0000313|Proteomes:UP000001882};
RN   [1] {ECO:0000313|Proteomes:UP000001882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17711 / JCM 13418 / NBRC 101707 / SANAE
RC   {ECO:0000313|Proteomes:UP000001882};
RX   PubMed=21829548; DOI=10.1371/journal.pone.0022898;
RA   Sakai S., Takaki Y., Shimamura S., Sekine M., Tajima T., Kosugi H.,
RA   Ichikawa N., Tasumi E., Hiraki A.T., Shimizu A., Kato Y., Nishiko R.,
RA   Mori K., Fujita N., Imachi H., Takai K.;
RT   "Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella
RT   paludicola, the first cultivated representative of the order
RT   Methanocellales.";
RL   PLoS ONE 6:E22898-E22898(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; AP011532; BAI61615.1; -; Genomic_DNA.
DR   AlphaFoldDB; D1YYU3; -.
DR   STRING; 304371.MCP_1543; -.
DR   KEGG; mpd:MCP_1543; -.
DR   eggNOG; arCOG02329; Archaea.
DR   eggNOG; arCOG02350; Archaea.
DR   eggNOG; arCOG06515; Archaea.
DR   InParanoid; D1YYU3; -.
DR   Proteomes; UP000001882; Chromosome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00075; HATPase; 1.
DR   CDD; cd00130; PAS; 3.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 3.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   NCBIfam; TIGR00229; sensory_box; 3.
DR   PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF08447; PAS_3; 2.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00086; PAC; 3.
DR   SMART; SM00091; PAS; 3.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50113; PAC; 3.
DR   PROSITE; PS50112; PAS; 3.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:BAI61615.1};
KW   Transferase {ECO:0000313|EMBL:BAI61615.1}.
FT   DOMAIN          22..94
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          98..150
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          174..206
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          224..275
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          276..346
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          350..401
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          412..628
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   628 AA;  70984 MW;  1ADCF9A0524B37E0 CRC64;
     MYEKVSRENE ERRRAEEALR EIKERYKLVI AGARGAIWDW DVPNKRVFYS PQWKALRGLS
     DDEATDREEE WSSRIHPEDA PRVMAAVQAH FEGRTPVFAE EYRTLCKDGS WKWISDRGMA
     QRDAHGRVVR MAGSENDITE RKHAEEALRD SEAHLNSIIR AVPTGIGVVV DRVITEANDN
     LCKMTGYTRD ELLGKDARIL YPSDEDYEYV GREKYDQINK YGTGTVETRW RRRDGSVIDI
     ILSSTPMDPG NLRAGVTFTA LDITERKRAE EAVRAADIRF RSLIQNSMDI IRILDREGRI
     IYESPSSDNI LGYPPGHTLG RSPLEFIHPD DRERVKNALG EVYDGRNPGT PTEFRIRKAD
     GSYLDVESTG KNMIGVPGVD GIVITTRPIT ERKRAEEALR VAKMQADLYV DLMCHDISNM
     NQVGMGFLEM ALDMLDLDEA GQEMLLKPRS AFENSSKLID NVRKLQKARS GEYPDREMDV
     GEVLGKVQDY YSRQHGPNVT INYPMNGGCV VRANELLYDL FSNLVGNAIK HSRAHPTIDI
     NVGPASENGH DYYRVTIDDR GPGIPDELKD VIFERKLTGD IKSKGSGIGL LMAKALTDSY
     KGRIWVEDRI PGDSAKGSRF VVMLPAIE
//