ID   D2ATV8_STRRD            Unreviewed;       900 AA.
AC   D2ATV8;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   SubName: Full=Alpha-mannosidase-like protein {ECO:0000313|EMBL:ACZ88613.1};
GN   OrderedLocusNames=Sros_5878 {ECO:0000313|EMBL:ACZ88613.1};
OS   Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI
OS   9100).
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Streptosporangium.
OX   NCBI_TaxID=479432 {ECO:0000313|EMBL:ACZ88613.1, ECO:0000313|Proteomes:UP000002029};
RN   [1] {ECO:0000313|EMBL:ACZ88613.1, ECO:0000313|Proteomes:UP000002029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100
RC   {ECO:0000313|Proteomes:UP000002029};
RX   PubMed=21304675; DOI=10.4056/sigs.631049;
RA   Nolan M., Sikorski J., Jando M., Lucas S., Lapidus A., Glavina Del Rio T.,
RA   Chen F., Tice H., Pitluck S., Cheng J.F., Chertkov O., Sims D., Meincke L.,
RA   Brettin T., Han C., Detter J.C., Bruce D., Goodwin L., Land M., Hauser L.,
RA   Chang Y.J., Jeffries C.D., Ivanova N., Mavromatis K., Mikhailova N.,
RA   Chen A., Palaniappan K., Chain P., Rohde M., Goker M., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Streptosporangium roseum type strain (NI
RT   9100).";
RL   Stand. Genomic Sci. 2:29-37(2010).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
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DR   EMBL; CP001814; ACZ88613.1; -; Genomic_DNA.
DR   RefSeq; WP_012892348.1; NC_013595.1.
DR   AlphaFoldDB; D2ATV8; -.
DR   STRING; 479432.Sros_5878; -.
DR   CAZy; GH38; Glycoside Hydrolase Family 38.
DR   KEGG; sro:Sros_5878; -.
DR   eggNOG; COG0383; Bacteria.
DR   HOGENOM; CLU_003442_2_1_11; -.
DR   Proteomes; UP000002029; Chromosome.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002029}.
FT   DOMAIN          5..218
FT                   /note="Glycoside hydrolase family 38 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01074"
FT   DOMAIN          531..732
FT                   /note="Glycosyl hydrolase family 38 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07748"
SQ   SEQUENCE   900 AA;  95514 MW;  EF962487C27E9C55 CRC64;
     MTPDIVVVPH THWDREWYLP FQRFRLGLVR MLDEVLDTMA ADPGYRFTMD GQLAALEDYL
     EIRPERLPAV RRLVAEGRFA AGPWLILADE FLCSGETLIR NLEYGMRGAA ELGGVMRVGY
     LPDQFGHCAQ MPQILRQAGL EHACLWRGVP ASVDRDAFAW IGADGTAVRT QYLPGGYGNA
     VALFSGPPQA LADRLAAFTE TLRPWHPAGP LLAMYGADHS APAADITAAG LRIATLHDYV
     TAQDPSVTDL PAVHGELRSH ARANILPGVI SARIPAKQAM ARAERVVTRY AEPLSALWLP
     GGTAAAKLLD MAWRRLIACS GHDSITGCGA DETAQQVAAR IAEAEQIGQA VVDMVSASLS
     DRASRDALVV VNPSPFPRTA LVLADLPESR AALSAPDGGR VPSQRLELAP TLLDETVMDD
     LTQLLGRIHE RELFGQEIVS WSADGDVFTI VVGRHATTGY DYADLRAAVL DGAAARPGPW
     RVRTCAEPVV TVAAHVTVAP FGRTVLTSVP APAPAQVPDG PGWARPAEGT LDNGLLRVTV
     APDGTLSLFA DGAEAHGVGR VVDGGDAGDT YNHAPPRADT LVDTPGRVEV ESVCTGPLVS
     VLEIRRDYAW PSAATPEGRS PVTENVTVTT RAELRAGEPY LRLEMSFDNR CRDHRVRWHA
     PLPSPAAESF SEGQLSIVRR GLTGEGGCGE EPLPTFPAEG FVTAGGLAVL LDQVTEYELT
     GGELALTLIR SVGLLSSNRN AYRDEPAGPQ LPTPAAQCPG PVTTRLAVLP HPGTWHEAGL
     PRLAEEYRHA LLAVPGSGRA AASPGAGGPG MSPEQAGASL AVEGTGVVLT ALRERGDVLE
     IRVVAEHPTA TEAVVRGPFG AARRADVLGV AGERLEVTGG VVRLPLRPFE IATLHLTRAG
//