ID D2AYB8_STRRD Unreviewed; 680 AA.
AC D2AYB8;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=RNA polymerase sigma factor containing a TPR repeat domain-like protein {ECO:0000313|EMBL:ACZ87128.1};
GN OrderedLocusNames=Sros_4226 {ECO:0000313|EMBL:ACZ87128.1};
OS Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI
OS 9100).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Streptosporangium.
OX NCBI_TaxID=479432 {ECO:0000313|EMBL:ACZ87128.1, ECO:0000313|Proteomes:UP000002029};
RN [1] {ECO:0000313|EMBL:ACZ87128.1, ECO:0000313|Proteomes:UP000002029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100
RC {ECO:0000313|Proteomes:UP000002029};
RX PubMed=21304675; DOI=10.4056/sigs.631049;
RA Nolan M., Sikorski J., Jando M., Lucas S., Lapidus A., Glavina Del Rio T.,
RA Chen F., Tice H., Pitluck S., Cheng J.F., Chertkov O., Sims D., Meincke L.,
RA Brettin T., Han C., Detter J.C., Bruce D., Goodwin L., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Ivanova N., Mavromatis K., Mikhailova N.,
RA Chen A., Palaniappan K., Chain P., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Streptosporangium roseum type strain (NI
RT 9100).";
RL Stand. Genomic Sci. 2:29-37(2010).
CC -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC {ECO:0000256|ARBA:ARBA00010641}.
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DR EMBL; CP001814; ACZ87128.1; -; Genomic_DNA.
DR AlphaFoldDB; D2AYB8; -.
DR STRING; 479432.Sros_4226; -.
DR KEGG; sro:Sros_4226; -.
DR eggNOG; COG4941; Bacteria.
DR eggNOG; COG4974; Bacteria.
DR HOGENOM; CLU_417781_0_0_11; -.
DR Proteomes; UP000002029; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR046531; DUF6596.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR47756:SF1; BLL0085 PROTEIN; 1.
DR PANTHER; PTHR47756; BLL6612 PROTEIN-RELATED; 1.
DR Pfam; PF20239; DUF6596; 1.
DR Pfam; PF02899; Phage_int_SAM_1; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF08281; Sigma70_r4_2; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000002029};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 437..516
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 532..680
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 680 AA; 73613 MW; 14AD1975209F0462 CRC64;
MTPRGSAAPG LRTSRGGALI VPMTARNVHG AIDAVWKFES ARIIAGLTRM VRDVGLAEEL
AQDALVAALE QWPGQGVPDN PGAWLMTTAK RRAIDHLRRG ERLERKHEEI AHALEQQGLE
EGVDDDVLRL MFVSCHPVLP AEARAALTLR LLGGLTALEI ARAFLVSEQA VAQRIAKAKR
TLAEERVPFE LPPGPELAGR LASVLEVIYL IFNEGYSATS GDDLMRPSLC LEALRLGRLL
AELAPRQAEV HGLVALMEIQ ASRSAARTGP SGEPIQLHEQ NRGRWDQLLI RRGFAAMLRA
KEAGGPPGPY VLQAAIAVSH AQAKTAQETD WGQIAALYGA LVRLVPSPVV QLNRAVALGM
ARGPQAGLDI VDTLTSDPAL KNYHLLSGVR GDFLAKLGRH DEARTEFERA ASLTHNAPER
AFLLRRAATG TTPVAGVTLG QAAESFLARE DLDAGTIRSY GQTLRRMCLD LGAGTPLAEV
TAGKLSTVFS VAWDGAAAKT WNRHRAAVRS FSSWASVDDL SAGLARKPES RERRPSIGPS
QLDALWERPG TALREKVLWR LLHESAAAAR TALSLNVEDL DLDDRRGRVA AKNGQVWLSW
QSGTARLLPH LVAGRTRGPL FLADRRPAPA RMPGPADLCP DTGRGRLSYE RAEYLFKQAT
RPLDPSGAGY TLHQLSHSRP
//
