ID D2B1G0_STRRD Unreviewed; 468 AA.
AC D2B1G0;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Xylosidase {ECO:0000313|EMBL:ACZ85425.1};
GN OrderedLocusNames=Sros_2447 {ECO:0000313|EMBL:ACZ85425.1};
OS Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI
OS 9100).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Streptosporangium.
OX NCBI_TaxID=479432 {ECO:0000313|EMBL:ACZ85425.1, ECO:0000313|Proteomes:UP000002029};
RN [1] {ECO:0000313|EMBL:ACZ85425.1, ECO:0000313|Proteomes:UP000002029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100
RC {ECO:0000313|Proteomes:UP000002029};
RX PubMed=21304675; DOI=10.4056/sigs.631049;
RA Nolan M., Sikorski J., Jando M., Lucas S., Lapidus A., Glavina Del Rio T.,
RA Chen F., Tice H., Pitluck S., Cheng J.F., Chertkov O., Sims D., Meincke L.,
RA Brettin T., Han C., Detter J.C., Bruce D., Goodwin L., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Ivanova N., Mavromatis K., Mikhailova N.,
RA Chen A., Palaniappan K., Chain P., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Streptosporangium roseum type strain (NI
RT 9100).";
RL Stand. Genomic Sci. 2:29-37(2010).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
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DR EMBL; CP001814; ACZ85425.1; -; Genomic_DNA.
DR RefSeq; WP_012889170.1; NC_013595.1.
DR AlphaFoldDB; D2B1G0; -.
DR STRING; 479432.Sros_2447; -.
DR CAZy; GH43; Glycoside Hydrolase Family 43.
DR KEGG; sro:Sros_2447; -.
DR eggNOG; COG3507; Bacteria.
DR HOGENOM; CLU_009397_6_0_11; -.
DR OrthoDB; 9758923at2; -.
DR Proteomes; UP000002029; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd18618; GH43_Xsa43E-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR43772:SF2; BETA-1,4-XYLOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR43772; ENDO-1,4-BETA-XYLANASE; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00022651};
KW Reference proteome {ECO:0000313|Proteomes:UP000002029};
KW Signal {ECO:0000256|SAM:SignalP};
KW Xylan degradation {ECO:0000256|ARBA:ARBA00022651}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..468
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003029350"
FT ACT_SITE 39
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 210
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 162
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 468 AA; 50087 MW; 55E40ACA1582298C CRC64;
MRRLRSGFLA VIAALGLVLA SAGPAPAAGP ITTAIYTADP AALVVGDTMY LHTGHDEAAP
GGTNFVMRDW HVFSSGDATT WTDNGAKLSI SNFGWAGADA WAGEVEPRNG KYYWYVPVNG
NGAGWMDIGV AVGDTPLGPF TDAKGGPLIS DGTPNSSPLN IDPTVFTDDD GQAYIYWGSY
YGLRAAKLKP DMVNLDGPVV TPAGVTNFWE APWMFKRNGT YYLAYAANDS GCSQPGYACI
RYATASNPLG PWTHRGVVLD QVTSTTNHPA IVEFKGQWYM VYHTAGAPGG GNFRRSVTLD
KLYWNADGTM RKVVQTTGPG GGGQPPTGTN HALTATASTS YVSPWETLGA IKDGAVPTGS
ADRSHGAYGN WDHRGTEWIE YQWPTARNIS RVATYWFDDD QGIDLPASCQ VQYWNGGSYV
DVPGQSSCGV AGDTYNVTTF NQVSTTRLRL KITSRSGYST GVLEWMAL
//
