ID D2B774_STRRD Unreviewed; 346 AA.
AC D2B774;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Alcohol dehydrogenase, zinc-containing {ECO:0000313|EMBL:ACZ89599.1};
GN OrderedLocusNames=Sros_6896 {ECO:0000313|EMBL:ACZ89599.1};
OS Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI
OS 9100).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Streptosporangium.
OX NCBI_TaxID=479432 {ECO:0000313|EMBL:ACZ89599.1, ECO:0000313|Proteomes:UP000002029};
RN [1] {ECO:0000313|EMBL:ACZ89599.1, ECO:0000313|Proteomes:UP000002029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100
RC {ECO:0000313|Proteomes:UP000002029};
RX PubMed=21304675; DOI=10.4056/sigs.631049;
RA Nolan M., Sikorski J., Jando M., Lucas S., Lapidus A., Glavina Del Rio T.,
RA Chen F., Tice H., Pitluck S., Cheng J.F., Chertkov O., Sims D., Meincke L.,
RA Brettin T., Han C., Detter J.C., Bruce D., Goodwin L., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Ivanova N., Mavromatis K., Mikhailova N.,
RA Chen A., Palaniappan K., Chain P., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Streptosporangium roseum type strain (NI
RT 9100).";
RL Stand. Genomic Sci. 2:29-37(2010).
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DR EMBL; CP001814; ACZ89599.1; -; Genomic_DNA.
DR RefSeq; WP_012893330.1; NC_013595.1.
DR AlphaFoldDB; D2B774; -.
DR STRING; 479432.Sros_6896; -.
DR KEGG; sro:Sros_6896; -.
DR eggNOG; COG2130; Bacteria.
DR HOGENOM; CLU_026673_29_2_11; -.
DR OrthoDB; 9805663at2; -.
DR Proteomes; UP000002029; Chromosome.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002029}.
FT DOMAIN 27..340
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 346 AA; 35653 MW; AB0E35581A81B7BB CRC64;
MSSNVTPDKQ IIGREIRLAS RPAGEPGPEN FELVRTEVPQ PGEGQILVRN TWMSVDPYMR
GRMDDAESYI PPFRLGAALE GGAVGEVVVS RSEAVAVGAT VSHFLGWREY AVMDASAATV
VDTAAVPAQA YLGALGTTGL TAYAALTEVA PVRRGDVVFV SGAAGAVGSV AGQLARKLGA
AKVIGSAGGP AKAEKLVTGF GFDAAIDYRA GSIAAQLAEA APEGIDVYLD NVGGDHLEAA
IGAIRHAGRI ALVGAISAYN ATAPVPGPDN LYRAAYKEAT LRGMLVTSYL HLFPEYIERA
AGWLADGTLH TEETVAEGIG QAPAAFLGVL RGANVGKMLV RLDGIG
//
