ID D2HX09_AILME Unreviewed; 234 AA.
AC D2HX09;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=MSP domain-containing protein {ECO:0000259|Pfam:PF00635};
DE Flags: Fragment;
GN ORFNames=PANDA_017114 {ECO:0000313|EMBL:EFB16437.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB16437.1};
RN [1] {ECO:0000313|EMBL:EFB16437.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL193583; EFB16437.1; -; Genomic_DNA.
DR RefSeq; XP_002927348.1; XM_002927302.3.
DR RefSeq; XP_019663570.1; XM_019808011.1.
DR RefSeq; XP_019663571.1; XM_019808012.1.
DR RefSeq; XP_019663572.1; XM_019808013.1.
DR AlphaFoldDB; D2HX09; -.
DR STRING; 9646.ENSAMEP00000015678; -.
DR GeneID; 100463603; -.
DR KEGG; aml:100463603; -.
DR CTD; 64598; -.
DR eggNOG; KOG0439; Eukaryota.
DR HOGENOM; CLU_088040_0_0_1; -.
DR InParanoid; D2HX09; -.
DR OMA; PPSARHF; -.
DR OrthoDB; 4837153at2759; -.
DR TreeFam; TF319778; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007507; P:heart development; IEA:Ensembl.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR039283; MOSPD1/3.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR PANTHER; PTHR34441; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR34441:SF4; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF00635; Motile_Sperm; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 175..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..118
FT /note="MSP"
FT /evidence="ECO:0000259|Pfam:PF00635"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..162
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 234
FT /evidence="ECO:0000313|EMBL:EFB16437.1"
SQ SEQUENCE 234 AA; 25499 MW; AC032CD1DCCD9B9B CRC64;
MRRGAPQDQE LVGPGAPGRG SRGAPPPSGL VPVLVFPPDL VFRADQRSGP RQLLTLYNPT
GAALRFRVLC TAPAKYTVFD AEGYVKPQSC IDIVIRHVAP IPSHYDVQDR FRIELSEEGT
EGRVVGRKDI TSVLRAPAYP LELQGQPNPT PHPGPPSWTA PPTARHFPEN RHPQLATSSF
LLFLLTGIVS VAFLLLPLQD ELGSQLPQIL HVSLGQKLVA AYVLGLLTMV FLRT
//
