ID D2PLR1_KRIFD Unreviewed; 1051 AA.
AC D2PLR1;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Transcriptional regulator, winged helix family {ECO:0000313|EMBL:ADB32491.1};
GN OrderedLocusNames=Kfla_3433 {ECO:0000313|EMBL:ADB32491.1};
OS Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Kribbellaceae; Kribbella.
OX NCBI_TaxID=479435 {ECO:0000313|EMBL:ADB32491.1, ECO:0000313|Proteomes:UP000007967};
RN [1] {ECO:0000313|Proteomes:UP000007967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17836 / JCM 10339 / NBRC 14399
RC {ECO:0000313|Proteomes:UP000007967};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M.,
RA Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA Pukall R., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Kribbella flavida DSM 17836.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADB32491.1, ECO:0000313|Proteomes:UP000007967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17836 / JCM 10339 / NBRC 14399
RC {ECO:0000313|Proteomes:UP000007967};
RX PubMed=21304701;
RA Pukall R., Lapidus A., Glavina Del Rio T., Copeland A., Tice H.,
RA Cheng J.-F., Lucas S., Chen F., Nolan M., LaButti K., Pati A., Ivanova N.,
RA Mavrommatis K., Mikhailova N., Pitluck S., Bruce D., Goodwin L., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C.D., Chen A., Palaniappan K., Chain P.,
RA Rohde M., Goeker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.-P., Brettin T.;
RT "Complete genome sequence of Kribbella flavida type strain (IFO 14399).";
RL Stand. Genomic Sci. 2:186-193(2010).
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; CP001736; ADB32491.1; -; Genomic_DNA.
DR RefSeq; WP_012921047.1; NC_013729.1.
DR AlphaFoldDB; D2PLR1; -.
DR STRING; 479435.Kfla_3433; -.
DR KEGG; kfl:Kfla_3433; -.
DR eggNOG; COG3629; Bacteria.
DR eggNOG; COG3903; Bacteria.
DR HOGENOM; CLU_004665_1_3_11; -.
DR OrthoDB; 3755432at2; -.
DR Proteomes; UP000007967; Chromosome.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000007967}.
FT DOMAIN 1..91
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..91
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 1051 AA; 113756 MW; 9AD2C45D0CC9964E CRC64;
MRIEVLGPVL AYADDGAPID LGGTRVRALL ARLALAGNEV VSVDSLLDGL WGDHSSGGTL
NALHALVHRL RKALAGAGVV ETVAGGYRLR LRSEQVDAVR FEQQAKRGSR ELAAGAAQPA
ASLLEEALAL WRGEALADVR TIPFAGTAGA RLDELRIGAL EDRFEAELRL GHHGEILADV
EAVAAAHPLR ERLAGLRMRA LHAAGRQSEA LAVFEGVRRT LAEELGVDPS EALRTTHLAV
LRGELDIPEA EQVRPEAVRG RLPAQLTRFV GREDELSLLA GSLETSRLVT VVGPGGVGKT
RLAVEAVSRH RAHQRGRVWL VSLAAVNTAD GLAEAVLGSL SVAEAQPSGT PLERVVNLLA
GGEGVLVLDN CEQISALVAE FAGQLLERQP YLTILATSRE PLEVMGETLC RLGPLDLPDA
HADAVRARES AAVRLFLDRA AAVQRSFVLD ASTAAPVVDI VRRLDGLPLA LELAAARLRT
MSAEQISRRL DDRFRLLCTG NRTAQPRQQT LHAVIEWSWD LLTSQERTLA RRMSVFPART
GVAVIEAVCA DSEEGLRADE VVDLLDSLVD KSIVEWAGDG YWMLETIRAH AADKLRLAAE
DEAVLRGLTR YFADLAEEHE PLLRSDKQAE SLRLFQAEYD NLMFALQTAI ENGDASDSAR
ILGPLYWYWV MHRYDARAEA YVAKVAEFGE ALPADARAAF TALHLIIGSG GPLTDRLGAL
IDDCVRTGAL RRYPMLLTIV LVMAPLLGLD ELAEREIARV RRGSDRWAIA CTFMIEAMWH
RGRGDRESST TAMATALHAF EEVGDRWWAA KALYGLAQNH AIAGDHDQAI TAYQDSLAIA
VDLGSQDEVS SRLGLATERM RAGDLTGAKR DIETAERAAW QRGQPALEIE ALGILAELYR
RSGEVQHADQ ELDRMETLIH KLPLAAEHAG NRLLLARVAN LLTAGNAVRA RELLPRAVHA
AQADRDAPLA AQLLARLLFL EGDPAGAATA LGLSEAVRGT FDHGDTELRW LAAALAERLG
RTDYETAYHR GADLTPHQAT DRLTTMAGAA P
//
