ID D2PXL6_KRIFD Unreviewed; 424 AA.
AC D2PXL6;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:ADB31658.1};
DE EC=3.2.1.51 {ECO:0000313|EMBL:ADB31658.1};
GN OrderedLocusNames=Kfla_2590 {ECO:0000313|EMBL:ADB31658.1};
OS Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Kribbellaceae; Kribbella.
OX NCBI_TaxID=479435 {ECO:0000313|EMBL:ADB31658.1, ECO:0000313|Proteomes:UP000007967};
RN [1] {ECO:0000313|Proteomes:UP000007967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17836 / JCM 10339 / NBRC 14399
RC {ECO:0000313|Proteomes:UP000007967};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M.,
RA Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA Pukall R., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Kribbella flavida DSM 17836.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADB31658.1, ECO:0000313|Proteomes:UP000007967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17836 / JCM 10339 / NBRC 14399
RC {ECO:0000313|Proteomes:UP000007967};
RX PubMed=21304701;
RA Pukall R., Lapidus A., Glavina Del Rio T., Copeland A., Tice H.,
RA Cheng J.-F., Lucas S., Chen F., Nolan M., LaButti K., Pati A., Ivanova N.,
RA Mavrommatis K., Mikhailova N., Pitluck S., Bruce D., Goodwin L., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C.D., Chen A., Palaniappan K., Chain P.,
RA Rohde M., Goeker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.-P., Brettin T.;
RT "Complete genome sequence of Kribbella flavida type strain (IFO 14399).";
RL Stand. Genomic Sci. 2:186-193(2010).
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
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DR EMBL; CP001736; ADB31658.1; -; Genomic_DNA.
DR RefSeq; WP_012920214.1; NC_013729.1.
DR AlphaFoldDB; D2PXL6; -.
DR STRING; 479435.Kfla_2590; -.
DR CAZy; GH29; Glycoside Hydrolase Family 29.
DR KEGG; kfl:Kfla_2590; -.
DR eggNOG; COG3669; Bacteria.
DR HOGENOM; CLU_002934_0_3_11; -.
DR OrthoDB; 5526311at2; -.
DR Proteomes; UP000007967; Chromosome.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000313|EMBL:ADB31658.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ADB31658.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007967}.
FT SITE 246
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 424 AA; 47690 MW; 2397CC13DA5FCE8B CRC64;
MAIQPWFEQA KLGIFLHYGI YAVNGIAESW SFFNGEISHE DYLEQLDGFT AAKFDADAWA
ELFAAAGARY AVLTSKHHDG VALYDTAAND LSTVKATPAR RDIVREYVDA LRRRDLRVGL
YFSHLDWSHP DYATVRPAGM PAGERGNPYA VPAAGEEDPE RWERFLAFHR AQLTEIVDRF
APDLLWFDGD WERDPEQWRM EEVRALIEAK LPEAVINGRM RGGFGDYATP EQGVPIVPPA
GPWELCVTIN DSWGFQHDDH HYKSVRQLIR LFAETIGGGG NLLLDVGPRE DGSIPAEQVE
RLRALGDWIR RHDRAVHGTT RGLPAGAFYG ASTISADRRR VYLFGFDRPN EYFVVRGLRN
KVLKATIVGS GVELRVDRQG GGIEGAAGWT YLYVDSDTAL DHHCTVVELE LDNELDLSEH
HTRD
//
