ID D2Q312_KRIFD Unreviewed; 1033 AA.
AC D2Q312;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Transcriptional regulator, SARP family {ECO:0000313|EMBL:ADB32137.1};
GN OrderedLocusNames=Kfla_3073 {ECO:0000313|EMBL:ADB32137.1};
OS Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Kribbellaceae; Kribbella.
OX NCBI_TaxID=479435 {ECO:0000313|EMBL:ADB32137.1, ECO:0000313|Proteomes:UP000007967};
RN [1] {ECO:0000313|Proteomes:UP000007967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17836 / JCM 10339 / NBRC 14399
RC {ECO:0000313|Proteomes:UP000007967};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M.,
RA Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA Pukall R., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Kribbella flavida DSM 17836.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADB32137.1, ECO:0000313|Proteomes:UP000007967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17836 / JCM 10339 / NBRC 14399
RC {ECO:0000313|Proteomes:UP000007967};
RX PubMed=21304701;
RA Pukall R., Lapidus A., Glavina Del Rio T., Copeland A., Tice H.,
RA Cheng J.-F., Lucas S., Chen F., Nolan M., LaButti K., Pati A., Ivanova N.,
RA Mavrommatis K., Mikhailova N., Pitluck S., Bruce D., Goodwin L., Land M.,
RA Hauser L., Chang Y.-J., Jeffries C.D., Chen A., Palaniappan K., Chain P.,
RA Rohde M., Goeker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.-P., Brettin T.;
RT "Complete genome sequence of Kribbella flavida type strain (IFO 14399).";
RL Stand. Genomic Sci. 2:186-193(2010).
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
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DR EMBL; CP001736; ADB32137.1; -; Genomic_DNA.
DR AlphaFoldDB; D2Q312; -.
DR STRING; 479435.Kfla_3073; -.
DR KEGG; kfl:Kfla_3073; -.
DR eggNOG; COG3629; Bacteria.
DR eggNOG; COG3903; Bacteria.
DR HOGENOM; CLU_004665_2_0_11; -.
DR Proteomes; UP000007967; Chromosome.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF17874; TPR_MalT; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 7.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091};
KW Reference proteome {ECO:0000313|Proteomes:UP000007967}.
FT DOMAIN 1..97
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..97
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 248..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1033 AA; 112343 MW; 2958914BCDAD2849 CRC64;
MVSADSPEIQ VRLFGQLVVT VAGQPVEISG GRARTLLAVL AVSTGEYVLA DTLADRLWGE
DLPRHVRRSM HTLVSRLRQV LGPTAIRTKA GGYALTLPPH QVDVLHFENL LRTAFAQPDH
ATELAGIKTA LKLWTGDPFD SVHSDWLSTV VTPRLVELYL SGVERRVDLD EAGVHAGELL
AGLRELAAAH PLRESLWARL LHVLSDCGRP AEALGLYDVI RSRLAKELGV GPGAQLQEVH
QRLLSDDAAR HVAVSSEPGA GPPPTDSRPT VHAEQLRGEP RSLPPDVPGF VGRTEQVEQL
AQSAGDRVMA LAAIDGMAGS GKTALAVHVA HQLAPRFPDG QLFIDLHGHT DGVEPVRPAE
ALGRLLQALG VPADQLPRHQ EDRAGLFRGL LAGRAVLLLL DNAADEAQLK PLLPGSRTCG
VLVTSRQRLA GLDTTATVSL DGLSPDEAVT LFCHVAGRHR LTDTSRQVLI QIAEQCGLLP
LAIRIAAARF RAHPSWEPQQ LLDLLRRHRD RLAELEAGPR SVAAAIDLSY RQLRPELRRA
YRLLGLHPGS DFTAESATAL LGSPATDDMR ELERLLDAHL LQERSFGRYS FHDLVKEHAG
RTVAVHESLQ GRREALGRLV DHYCRSTTAA VRLLYPDRAE NLPIHQPVQV PPATAEQAST
WLKAELSTVL AVAEHTVTAD RPACARHLAD TLYVYFRTVG RSAELQSLHR QAREVARAVG
DTAGEAESSI RLGECLRLRG AHASAFVEYA EALQLADAAG HRHGKMAALH GRGLVHGILD
RNDEGLRDLM KALDLADELG NPAGMLDALN GLSWIHGKRG EVAQAMVYNE RALEIARSVR
HRSLGKLLSA AGHHHLRQGD PARAMGMFEQ ALQEARTNGN RHNELRCLDG LAESHRLLGD
LSAAADCYHN ALQLARELGS PNWELEAHQG IGRLELALGH AEEALVRHQQ ALDVASALCQ
PVDQARAHDG LAHALEKLGD VEGAAHHWVH ALTILAAIGV THTDEWQVRI ATLQDHVDRI
SPLMELPGRR RSR
//
