ID   D2QAT2_BIFDB            Unreviewed;       290 AA.
AC   D2QAT2;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   SubName: Full=rRNA methylase {ECO:0000313|EMBL:ADB09918.1};
DE            EC=2.1.1.66 {ECO:0000313|EMBL:ADB09918.1};
GN   OrderedLocusNames=BDP_1300 {ECO:0000313|EMBL:ADB09918.1};
OS   Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1).
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=401473 {ECO:0000313|EMBL:ADB09918.1, ECO:0000313|Proteomes:UP000008693};
RN   [1] {ECO:0000313|EMBL:ADB09918.1, ECO:0000313|Proteomes:UP000008693}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27534 / DSM 20436 / JCM 1195 / Bd1
RC   {ECO:0000313|Proteomes:UP000008693};
RX   PubMed=20041198; DOI=10.1371/journal.pgen.1000785;
RA   Ventura M., Turroni F., Zomer A., Foroni E., Giubellini V., Bottacini F.,
RA   Canchaya C., Claesson M.J., He F., Mantzourani M., Mulas L., Ferrarini A.,
RA   Gao B., Delledonne M., Henrissat B., Coutinho P., Oggioni M., Gupta R.S.,
RA   Zhang Z., Beighton D., Fitzgerald G.F., O'Toole P.W., van Sinderen D.;
RT   "The Bifidobacterium dentium Bd1 genome sequence reflects its genetic
RT   adaptation to the human oral cavity.";
RL   PLoS Genet. 5:E1000785-E1000785(2009).
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DR   EMBL; CP001750; ADB09918.1; -; Genomic_DNA.
DR   RefSeq; WP_003839872.1; NC_013714.1.
DR   AlphaFoldDB; D2QAT2; -.
DR   STRING; 401473.BDP_1300; -.
DR   GeneID; 69536537; -.
DR   KEGG; bde:BDP_1300; -.
DR   eggNOG; COG0566; Bacteria.
DR   HOGENOM; CLU_021322_3_1_11; -.
DR   Proteomes; UP000008693; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd18095; SpoU-like_rRNA-MTase; 1.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR013123; SpoU_subst-bd.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR43191:SF16; RNA METHYLASE-RELATED; 1.
DR   PANTHER; PTHR43191; RRNA METHYLTRANSFERASE 3; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   SMART; SM00967; SpoU_sub_bind; 1.
DR   SUPFAM; SSF75217; alpha/beta knot; 1.
DR   SUPFAM; SSF55315; L30e-like; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:ADB09918.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008693};
KW   Transferase {ECO:0000313|EMBL:ADB09918.1}.
FT   DOMAIN          35..116
FT                   /note="RNA 2-O ribose methyltransferase substrate binding"
FT                   /evidence="ECO:0000259|SMART:SM00967"
SQ   SEQUENCE   290 AA;  31306 MW;  C902F3D8FF33B627 CRC64;
     MPIKTEVIAN PKAERIRRVA ELAERKGRKR AGRFLVEGPQ SVRELLTWHP DIVRDLYVEA
     IGTEPDAPFL TDTVAQMAGK AMQAGAYVHK VTHAVMRHMS SDAQGVLAVA DMQGFLDAAG
     NVESFGDNAM VAAFWQVRDP GNAGTVIRSA DAAGCAAVVF VDECVDIFNP KVIRSTAGSL
     FHLPVLTMGT EAFFAWCDER NLAIYAADVY GTDSRPPEPL TDVLAEPSTL AGAKTMIFGN
     EARGLTREVL DRTDRIVSIP IYGKAESLNL GTSAAVMLLS LAMSSHVERM
//