ID D2R810_PIRSD Unreviewed; 322 AA.
AC D2R810;
DT 02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT 02-MAR-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=NAD-dependent epimerase/dehydratase {ECO:0000313|EMBL:ADB19341.1};
GN OrderedLocusNames=Psta_4699 {ECO:0000313|EMBL:ADB19341.1};
OS Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128) (Pirella
OS staleyi).
OC Bacteria; Planctomycetota; Planctomycetia; Pirellulales; Pirellulaceae;
OC Pirellula.
OX NCBI_TaxID=530564 {ECO:0000313|EMBL:ADB19341.1, ECO:0000313|Proteomes:UP000001887};
RN [1] {ECO:0000313|EMBL:ADB19341.1, ECO:0000313|Proteomes:UP000001887}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27377 / DSM 6068 / ICPB 4128
RC {ECO:0000313|Proteomes:UP000001887};
RX PubMed=21304671; DOI=10.4056/sigs.51657;
RA Clum A., Tindall B.J., Sikorski J., Ivanova N., Mavrommatis K., Lucas S.,
RA Glavina del Rio T., Nolan M., Chen F., Tice H., Pitluck S., Cheng J.F.,
RA Chertkov O., Brettin T., Han C., Detter J.C., Kuske C., Bruce D.,
RA Goodwin L., Ovchinikova G., Pati A., Mikhailova N., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Chain P.,
RA Rohde M., Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P., Lapidus A.;
RT "Complete genome sequence of Pirellula staleyi type strain (ATCC 27377).";
RL Stand. Genomic Sci. 1:308-316(2009).
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
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DR EMBL; CP001848; ADB19341.1; -; Genomic_DNA.
DR RefSeq; WP_012913600.1; NC_013720.1.
DR AlphaFoldDB; D2R810; -.
DR STRING; 530564.Psta_4699; -.
DR KEGG; psl:Psta_4699; -.
DR eggNOG; COG0451; Bacteria.
DR HOGENOM; CLU_007383_4_0_0; -.
DR OrthoDB; 258549at2; -.
DR UniPathway; UPA00796; UER00771.
DR Proteomes; UP000001887; Chromosome.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0048040; F:UDP-glucuronate decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0042732; P:D-xylose metabolic process; IEA:InterPro.
DR GO; GO:0033320; P:UDP-D-xylose biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd05230; UGD_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR044516; UXS.
DR PANTHER; PTHR43078:SF6; UDP-GLUCURONIC ACID DECARBOXYLASE 1; 1.
DR PANTHER; PTHR43078; UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001887}.
FT DOMAIN 5..232
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 322 AA; 36315 MW; 1D981C1967FFC0FE CRC64;
MIKRILVTGG AGFLGSHLCE RLVDLGHDVV CLDNFFTSQK TNVAHLLGRP NFDLIRHDIT
SPIWLEVDEI YNLACPAAPG HYQFNPIKTM KTSVLGMINM LGMARRCKAK VLQASTSEVY
GDPEVHPQVE SYRGNVNPIG IRACYDEGKR AAETLMMDYH RSNGINIRIV RIFNTYGPRM
HPFDGRVVSN FIRQALTGED LTIFGNGDQT RSFCFRDDLV EGLIRMMHAS DSFTGPCNLG
NPDEFTVREL AELVLELTGS KSKIVSLPLP ADDPVRRRPD ITLAKTNLDW QPMVPLKEGL
RRTIEWFRSV NISHYRPPTP NF
//
